| 题名 | Genetically encoded single circularly permuted fluorescent protein-based intensity indicators |
| 作者 | |
| 通讯作者 | Wang, Liang |
| 发表日期 | 2020
|
| DOI | |
| 发表期刊 | |
| ISSN | 13616463
|
| EISSN | 1361-6463
|
| 卷号 | 53期号:11 |
| 摘要 | Fluorescent protein (FP)-based genetically encoded indicators are valuable tools for reporting signaling activities with high spatial-temporal resolution in living cells and animal models. Thereinto, single circularly permuted FP-based intensity sensors (cpFP sensors or cpFP-based sensors, unless otherwise specified) are of particular interest due to their unprecedented high sensitivity and fast kinetics. In this review, we summarized the recent progress with cpFP sensors, focusing on the practical considerations in sensor development and usage, and categorization of cpFP sensors. We also discuss future directions in improvement of existing sensors, development of new sensors, and functional super-resolution imaging with cpFP sensors. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 其他
|
| 资助项目 | [JCYJ20170818164040422]
; National Basic Research Program of China (973 Program)[2017YFA0700403]
; Chinese Academy of Sciences[GJJSTD20180002]
; National Natural Science Foundation of China[2018M633180]
|
| WOS研究方向 | Physics
|
| WOS类目 | Physics, Applied
|
| WOS记录号 | WOS:000519131400001
|
| 出版者 | |
| EI入藏号 | 20200808197162
|
| EI主题词 | Cell Signaling
; Fluorescence
|
| EI分类号 | Biomedical Engineering:461.1
; Light/optics:741.1
; Organic Compounds:804.1
|
| ESI学科分类 | PHYSICS
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：10
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/104729 |
| 专题 | 南方科技大学医院 生命科学学院 生命科学学院_生物系 |
| 作者单位 | 1.Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen; 518055, China 2.Department of Ophthalmology, Southern University of Science and Technology Hospital, Shenzhen; 518055, China 3.Department of Biology, Southern University of Science and Technology, Shenzhen; 518055, China 4.CAS Key Laboratory of Health Informatics, Shenzhen Institute of Synthetic Biology, Shenzhen-Hong Kong Institute of Brain Science, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen; 518055, China |
| 推荐引用方式 GB/T 7714 |
Liu, Wenfeng,Deng, Mengying,Yang, Chengming,et al. Genetically encoded single circularly permuted fluorescent protein-based intensity indicators[J]. Journal of Physics D: Applied Physics,2020,53(11).
|
| APA |
Liu, Wenfeng.,Deng, Mengying.,Yang, Chengming.,Liu, Feng.,Guan, Xinmeng.,...&Chu, Jun.(2020).Genetically encoded single circularly permuted fluorescent protein-based intensity indicators.Journal of Physics D: Applied Physics,53(11).
|
| MLA |
Liu, Wenfeng,et al."Genetically encoded single circularly permuted fluorescent protein-based intensity indicators".Journal of Physics D: Applied Physics 53.11(2020).
|
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
;
修改评论