南方科技大学知识苑(SUSTech KC): Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha 8-mediated activation of RhoA signaling pathway

题名	Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha 8-mediated activation of RhoA signaling pathway
作者	Cai, Qingxian 1; Chen, Fengjuan 2; Xu, Fen 3; Wang, Ke 4; Zhang, Ka 4; Li, Guojun 1; Chen, Jun1 ; Deng, Hong 4; He, Qing 1
通讯作者	Deng, Hong; He, Qing
发表日期	2020-03
DOI	10.1016/j.metabol.2020.154140
发表期刊	METABOLISM-CLINICAL AND EXPERIMENTAL 影响因子和分区
ISSN	0026-0495
EISSN	1532-8600
卷号	104
摘要	Background: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases that may progress to liver fibrosis or cancer. The present study aimed to investigate the role of microRNA-125b-5p (miR-125b-5p) in NAFLD and to further explore underlying molecular mechanisms.
关键词	microRNA-125b-5p ITGA8 The RhoA signaling pathway Nonalcoholic fatty liver disease Liver fibrosis
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	National Natural Science Foundation of China[81870597]
WOS研究方向	Endocrinology & Metabolism
WOS类目	Endocrinology & Metabolism
WOS记录号	WOS:000518471400009
出版者	W B SAUNDERS CO-ELSEVIER INC
ESI学科分类	BIOLOGY & BIOCHEMISTRY
来源库	Web of Science
引用统计	被引频次[WOS]：26
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/104756
专题	南方科技大学第二附属医院
作者单位	1.Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Dept Hepatopathy, Affiliated Hosp 2, 29 Bulan Rd, Shenzhen 518112, Peoples R China 2.Guangzhou Eighth Peoples Hosp, Dept Hepatopathy, Guangzhou 510080, Peoples R China 3.Sun Yat Sen Univ, Dept Endocrinol, GuangdongProv Key Lab Diabetol, Affiliated Hosp 3, Guangzhou 510630, Peoples R China 4.Sun Yat Sen Univ, Dept Infect Dis, Affiliated Hosp 3, 600 Tianhe Rd, Guangzhou 510630, Peoples R China
第一作者单位	南方科技大学第二附属医院
通讯作者单位	南方科技大学第二附属医院
第一作者的第一单位	南方科技大学第二附属医院
推荐引用方式 GB/T 7714	Cai, Qingxian,Chen, Fengjuan,Xu, Fen,et al. Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha 8-mediated activation of RhoA signaling pathway[J]. METABOLISM-CLINICAL AND EXPERIMENTAL,2020,104.
APA	Cai, Qingxian.,Chen, Fengjuan.,Xu, Fen.,Wang, Ke.,Zhang, Ka.,...&He, Qing.(2020).Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha 8-mediated activation of RhoA signaling pathway.METABOLISM-CLINICAL AND EXPERIMENTAL,104.
MLA	Cai, Qingxian,et al."Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin alpha 8-mediated activation of RhoA signaling pathway".METABOLISM-CLINICAL AND EXPERIMENTAL 104(2020).