| 题名 | A mitochondria-targeting NIR fluorescent potassium ion sensor: Real-time investigation of the mitochondrial K+regulation of apoptosisin situ |
| 作者 | |
| 通讯作者 | Su，Fengyu; Chen，Meiwan; Tian，Yanqing |
| 发表日期 | 2020-05-18
|
| DOI | |
| 发表期刊 | |
| ISSN | 1359-7345
|
| EISSN | 1364-548X
|
| 卷号 | 56期号:40页码:5405-5408 |
| 摘要 | The first NIR fluorescent mitochondria-targeting Ksensor, denoted asTAC-Rh, was developed. The produced sensor consists of a rhodamine analog as the fluorophore and triazacryptand (TAC) as the Krecognition unit. Compared to the Ksensors reported previously,TAC-Rhexhibits two unique optical properties: the largest Stokes shifts (120 nm) and the longest emission peak wavelength (720 nm). With the assistance of this novel sensor, real-time changes of Kconcentrations in mitochondria during apoptosis were monitored for the first time. Moreover, it was also the first time that the relationship between mitochondrial Kflux and apoptosis was investigated in real time using fluorescence imaging. |
| 相关链接 | [Scopus记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | NI论文
|
| 学校署名 | 第一
; 通讯
|
| 资助项目 | National Natural Science Foundation of China[21774054][21574061]
; Shenzhen fundamental research programs[JCYJ20170412152922553]
; Macao Science and Technology Development Fund[083/2017/A2]
; University of Macau[MYRG2016-00130-ICMS-QRCM][MYRG2017-00182-ICMS]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Multidisciplinary
|
| WOS记录号 | WOS:000536772700013
|
| 出版者 | |
| EI入藏号 | 20202308782961
|
| EI主题词 | Fluorescence imaging
; Potassium
; Mitochondria
; Infrared devices
; Optical properties
|
| EI分类号 | Biological Materials and Tissue Engineering:461.2
; Biology:461.9
; Alkali Metals:549.1
; Light/Optics:741.1
; Imaging Techniques:746
|
| ESI学科分类 | CHEMISTRY
|
| Scopus记录号 | 2-s2.0-85084940205
|
| 来源库 | Scopus
|
| 引用统计 |
被引频次[WOS]：21
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/138147 |
| 专题 | 工学院_材料科学与工程系 前沿与交叉科学研究院 |
| 作者单位 | 1.Department of Materials Science and Engineering Southern University of Science and Technology,Shenzhen,518055,China 2.State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical Sciences,University of Macau,999078,Macao 3.Academy for Advanced Interdisciplinary Studies Southern University of Science and Technology,Shenzhen,518055,China |
| 第一作者单位 | 材料科学与工程系 |
| 通讯作者单位 | 前沿与交叉科学研究院; 材料科学与工程系 |
| 第一作者的第一单位 | 材料科学与工程系 |
| 推荐引用方式 GB/T 7714 |
Song，Guangjie,Jiang，Di,Wang，Lei,et al. A mitochondria-targeting NIR fluorescent potassium ion sensor: Real-time investigation of the mitochondrial K+regulation of apoptosisin situ[J]. CHEMICAL COMMUNICATIONS,2020,56(40):5405-5408.
|
| APA |
Song，Guangjie.,Jiang，Di.,Wang，Lei.,Ning，Juewei.,Sun，Xiangzhong.,...&Tian，Yanqing.(2020).A mitochondria-targeting NIR fluorescent potassium ion sensor: Real-time investigation of the mitochondrial K+regulation of apoptosisin situ.CHEMICAL COMMUNICATIONS,56(40),5405-5408.
|
| MLA |
Song，Guangjie,et al."A mitochondria-targeting NIR fluorescent potassium ion sensor: Real-time investigation of the mitochondrial K+regulation of apoptosisin situ".CHEMICAL COMMUNICATIONS 56.40(2020):5405-5408.
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| 条目包含的文件 | 条目无相关文件。 | |||||
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