Obstacle-free planar hybrid micromixer with low pressure drop

Bazaz, Sajad Razavi1,2; Amiri, Hoseyn A.3,4,5; Vasilescu, Steven1; Mehrizi, Ali Abouei6; Jin, Dayong2,7; Miansari, Morteza3,5; Warkiani, Majid Ebrahimi1,2,7,8

2020-07-15

10.1007/s10404-020-02367-x

Microfluidics and Nanofluidics   影响因子和分区

1613-4982

1613-4990

Planar micromixers with repetitive units have received substantial research interest since they allow low cost, lab-on-a-chip (LOC), and point-of-care (POC) systems to achieve a proper level of mixing for any given process. This paper presents an efficient planar micromixer that combines four types of mixing units, including convergent-divergent, circular, rhombic, and G-shaped micromixers. Their combinations and resulting effects on the mixing efficiency are numerically and experimentally investigated. A comprehensive Taguchi design of experiment method was used to reduce the number of the combinations from 1024 to only 16, among which a micromixer made of rhombic and G-shaped units readily showed a mixing efficiency beyond 80% over a wide range of inlet Reynolds numbers 0.001-0.3 and 35-65; meanwhile, a pressure drop as low as 12 kPa was reported. The velocity and concentration fields and their gradients within the nominated micromixer were analyzed, providing a better understanding of the mixing mechanism. These results offer design insights for further development of planar micromixers with repetitive unites for low-cost LOC and POC devices.

Planar mixing units Optimization Numerical simulation Chaotic advection Mixing index Pressure drop

SCI ; EI

英语

通讯

Australian Research Council[DP170103704][DP180103003] ; National Health and Medical Research Council through the Career Development Fellowship[APP1143377]

Science & Technology - Other Topics ; Instruments & Instrumentation ; Physics

Nanoscience & Nanotechnology ; Instruments & Instrumentation ; Physics, Fluids & Plasmas

WOS:000548640100001

SPRINGER HEIDELBERG

20202908952774

Efficiency ; Mixers (machinery) ; Reynolds number ; Costs ; Drops ; Lab-on-a-chip ; Design of experiments ; Mixing

Fluid Flow, General:631.1 ; Semiconductor Devices and Integrated Circuits:714.2 ; Chemical Operations:802.3 ; Engineering Research:901.3 ; Cost and Value Engineering; Industrial Economics:911 ; Production Engineering:913.1

Web of Science

1.Univ Technol Sydney, Sch Biomed Engn, Sydney, NSW 2007, Australia
2.Univ Technol Sydney, Fac Sci, Inst Biomed Mat & Devices IBMD, Sydney, NSW 2007, Australia
3.Babol Noshirvani Univ Technol, Dept Mech Engn, Micro Nanosyst & Appl Biophys Lab, Babol Sar 484, Iran
4.Iran Univ Sci & Technol, Sch Mech Engn, Sensors & Integrated BioMEMS Microfluid Lab, Tehran, Iran
5.ACECR, Royan Inst Stem Cell Biol & Technol, Dept Canc Med, Cell Sci Res Ctr, Isar 11, Babol Sar 4713818983, Iran
6.Univ Tehran, Fac New Sci & Technol, Dept Life Sci Engn, Tehran, Iran
7.Southern Univ Sci & Technol, SUStech UTS Joint Res Ctr Biomed Mat & Devices, Shenzhen 518055, Peoples R China
8.Sechenov Univ, Inst Mol Med, Moscow 119991, Russia

Bazaz, Sajad Razavi,Amiri, Hoseyn A.,Vasilescu, Steven,et al. Obstacle-free planar hybrid micromixer with low pressure drop[J]. Microfluidics and Nanofluidics,2020,24(8).

Bazaz, Sajad Razavi.,Amiri, Hoseyn A..,Vasilescu, Steven.,Mehrizi, Ali Abouei.,Jin, Dayong.,...&Warkiani, Majid Ebrahimi.(2020).Obstacle-free planar hybrid micromixer with low pressure drop.Microfluidics and Nanofluidics,24(8).

Bazaz, Sajad Razavi,et al."Obstacle-free planar hybrid micromixer with low pressure drop".Microfluidics and Nanofluidics 24.8(2020).