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题名

Experimental Study of Recombinant Adenovirus Ad- EGFP Transfected Rat Cornea

作者
通讯作者Shen, Xiaoli
发表日期
2020
发表期刊
ISSN
0798-2259
卷号30期号:5页码:2287-2294
摘要
To investigate the effect of recombinant adenovirus ad EGFP on cornea of rats and analyze its mechanism. 60 healthy rats were selected, 30 rats were transfected with recombinant adenovirus ad EGFP as the observation group, and 30 rats in the control group were injected with normal saline. The expression of ad EGFP protein, IgA, a value (copy number / UG total RNA) and ad EGFP mRNA were compared between the two groups. Compared with the control group, the expression of ad EGFP protein, IgA in cornea, a value in cornea and the expression of ad EGFP mRNA were significantly higher in the observation group (P < 0.05).Conclusion The recombinant adenovirus ad EGFP can be successfully transfected into rat cornea, which is safe and effective.
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语种
英语
学校署名
其他
资助项目
Medical Science and Technology Research Fund Project of Guangdong Province[A2015315]
WOS研究方向
Veterinary Sciences
WOS类目
Veterinary Sciences
WOS记录号
WOS:000547779800003
出版者
来源库
Web of Science
引用统计
被引频次[WOS]:0
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/141441
专题南方科技大学第一附属医院
作者单位
1.Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Dept Ophthalmol, Shenzhen 518020, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518020, Peoples R China
3.Shenzhen Univ, Shenzhen Eye Hosp, Shenzhen Key Lab Ophthalmol, Sch Med, Shenzhen 518000, Peoples R China
4.Shenzhen Aier Eye Hosp, Shenzhen 510000, Guangdong, Peoples R China
第一作者单位南方科技大学第一附属医院
推荐引用方式
GB/T 7714
Li, Qiang,Nie, Ai-qin,Wang, Xuejiao,et al. Experimental Study of Recombinant Adenovirus Ad- EGFP Transfected Rat Cornea[J]. REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS,2020,30(5):2287-2294.
APA
Li, Qiang,Nie, Ai-qin,Wang, Xuejiao,Huang, Lina,&Shen, Xiaoli.(2020).Experimental Study of Recombinant Adenovirus Ad- EGFP Transfected Rat Cornea.REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS,30(5),2287-2294.
MLA
Li, Qiang,et al."Experimental Study of Recombinant Adenovirus Ad- EGFP Transfected Rat Cornea".REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS 30.5(2020):2287-2294.
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