Toxicity evaluation and by-products identification of triclosan ozonation and chlorination

Li，Liping1,2,3

2021

10.1016/j.chemosphere.2020.128223

CHEMOSPHERE   影响因子和分区

0045-6535

1879-1298

Triclosan (TCS) has attracted increasing concern due to its ubiquitous occurrence in aquatic environments as well as its potential adverse effects on human health. This study investigated the toxicity and transformation characteristics of triclosan ozonation and chlorination. The results showed that two hydroxylated by-products were formed via nucleophilic substitution during ozonation, while three chlorinated compounds were generated via electrophilic substitution during chlorination. The toxicity results demonstrated that the parent compound, triclosan, exhibited mild genotoxicity and anti-estrogenic activity. The chlorination of triclosan resulted in a 30-fold increase in anti-estrogenic activity owing to the generation of toxic polychlorinated transformation by-products. In addition, the chlorination by-products were found to be genotoxic like the parent compound. Fortunately, in contrast to chlorination, ozonation could mitigate the genotoxicity and anti-estrogenic activity of triclosan-containing water.

Chlorination Formation mechanisms Ozonation Toxicity Triclosan

SCI ; EI

英语

第一 ; 通讯

China Postdoctoral Science Foundation[2018M642916]

Environmental Sciences & Ecology

Environmental Sciences

WOS:000595802200286

PERGAMON-ELSEVIER SCIENCE LTD

20203709171389

Ozone ; Toxicity ; Ozonization

Health Care:461.7 ; Chemical Reactions:802.2 ; Chemical Products Generally:804

ENVIRONMENT/ECOLOGY

2-s2.0-85090403208

Scopus

1.State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control,School of Environmental Science and Engineering,Southern University of Science and Technology,Shenzhen,518055,China
2.Division of Environment and Sustainability,The Hong Kong University of Science and Technology,Kowloon,Clear Water Bay,Hong Kong
3.State Key Laboratory of Information Engineering in Surveying,Mapping and Remote Sensing,Wuhan University,Wuhan,China

Li，Liping. Toxicity evaluation and by-products identification of triclosan ozonation and chlorination[J]. CHEMOSPHERE,2021,263.

Li，Liping.(2021).Toxicity evaluation and by-products identification of triclosan ozonation and chlorination.CHEMOSPHERE,263.

Li，Liping."Toxicity evaluation and by-products identification of triclosan ozonation and chlorination".CHEMOSPHERE 263(2021).