Liquid-phase exfoliation of black sesame to create a nanoplatform forin vitrophotoluminescence and photothermal therapy

Xie, Zhongjian1; Lu, Ruitao2; Zhu, Yao3,4; Peng, Minhua1,5; Fan, Taojian6,7,8; Ren, Peigen5; Wang, Bing9; Kang, Lin10,11,12; Liu, Xiaoyun13; Li, Sha14; Cui, Huixian14

2020-09

10.2217/nnm-2020-0151

Nanomedicine   影响因子和分区

1743-5889

1748-6963

Aim:The present study aims to apply the facile liquid-phase exfoliation (LPE) strategy to fabricate 2D organic materials and thus to broaden the family of biocompatible and multifunctional 2D materials.Materials & methods:2D material-organic melanin and cellulose nanosheets were synthesized from black sesame hull using LPE. Photoluminescence and photothermal properties of the nanosheets were assessed, as well as stability and cell killing ability.Results:The prepared 2D nanoplatform exhibited broad and multiple photoluminescent emission bands. It also demonstrated efficient photothermal cancer therapy with excellent biocompatibility.Conclusion:The present study could open an avenue in exfoliating organic materials using the LPE strategy. This could make the fabrication of multifunctional 2D organic materials more efficient and broaden the family of biocompatible 2D nanomaterials.

2D organic nanomaterials biocompatibility black sesame liquid-phase exfoliation LPE melanin and cellulose nanosheets photoluminescent photothermal

SCI

英语

其他

State Key Research Development Program of China[2019YFB2203503] ; National Natural Science Fund[61875138][61435010][81871358][U1801254][61961136001] ; Science and Technology Innovation Commission of Shenzhen[KQTD2015032416270385][JCYJ20180307164612205][GJHZ20180928160209731] ; Shenzhen Overseas High-Caliber Peacock Foundation[KQTD2015071414385495] ; Shenzhen Science and Innovation Commission Project Grants[JCYJ20170411094933148][JCYJ20170815113109175] ; Guangdong Basic and Applied Basic Research Foundation[2019B1515120043][2019A1515111132] ; Natural Science Foundation of Guangdong Province[2020A151501612] ; Longhua District Science and Innovation Commission Project[JCYJ201904]

Biotechnology & Applied Microbiology ; Science & Technology - Other Topics

Biotechnology & Applied Microbiology ; Nanoscience & Nanotechnology

WOS:000567278200001

FUTURE MEDICINE LTD

Web of Science

1.Shenzhen Int Inst Biomed Res, Shenzhen 518116, Guangdong, Peoples R China
2.Guangzhou Med Univ, Sch Basic Med Sci, Guangzhou 511436, Guangdong, Peoples R China
3.Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Dept Ultrasonog, Shenzhen 518020, Guangdong, Peoples R China
4.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518055, Guangdong, Peoples R China
5.Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Guangdong, Peoples R China
6.Shenzhen Univ, Hlth Sci Ctr,Inst Microscale Optoelect, Shenzhen Peoples Hosp 2,Minist Educ & Guangdong P, Affiliated Hosp 1,Key Lab Optoelect Devices & Sys, Shenzhen 518060, Peoples R China
7.Shenzhen Univ, Hlth Sci Ctr, Shenzhen Peoples Hosp 2, Affiliated Hosp 1,Otolaryngol Dept, Shenzhen 518060, Peoples R China
8.Shenzhen Univ, Hlth Sci Ctr, Shenzhen Peoples Hosp 2, Affiliated Hosp 1,Biobank, Shenzhen 518060, Peoples R China
9.Shenzhen Univ, Coll Phys & Optoelect Engn, Shenzhen 518060, Peoples R China
10.Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Clin Med Res Ctr, Shenzhen 518020, Guangdong, Peoples R China
11.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518020, Guangdong, Peoples R China
12.Shenzhen Peoples Hosp, Dept Endocrinol, Shenzhen 518020, Guangdong, Peoples R China
13.Hebei Med Univ, Dept Neurol, Hosp 2, 215 West Heping Rd, Shijiazhuang 050000, Hebei, Peoples R China
14.Hebei Med Univ, Dept Anat, Shijiazhuang, Hebei, Peoples R China

Xie, Zhongjian,Lu, Ruitao,Zhu, Yao,et al. Liquid-phase exfoliation of black sesame to create a nanoplatform forin vitrophotoluminescence and photothermal therapy[J]. Nanomedicine,2020,15(21):2041-2052.

Xie, Zhongjian.,Lu, Ruitao.,Zhu, Yao.,Peng, Minhua.,Fan, Taojian.,...&Cui, Huixian.(2020).Liquid-phase exfoliation of black sesame to create a nanoplatform forin vitrophotoluminescence and photothermal therapy.Nanomedicine,15(21),2041-2052.

Xie, Zhongjian,et al."Liquid-phase exfoliation of black sesame to create a nanoplatform forin vitrophotoluminescence and photothermal therapy".Nanomedicine 15.21(2020):2041-2052.