Comparison of Common Methods for Precision Volume Measurement of Hematoma

Chen, Minhong1; Li, Zhong1; Ding, Jianping2; Lu, Xingqi2; Cheng, Yinan3; Lin, Jiayun1

2020-07-17

10.1155/2020/6930836

Computational and Mathematical Methods in Medicine   影响因子和分区

1748-670X

1748-6718

Purpose. Our aim is to conduct analysis and comparison of some methods commonly used to measure the volume of hematoma, for example, slice method, voxelization method, and 3D-Slicer software method (projection method).Method. In order to validate the accuracy of the slice method, voxelization method, and 3D-Slicer method, these three methods were first applied to measure two known volumetric models, respectively. Then, a total of 198 patients diagnosed with spontaneous intracerebral hemorrhage (ICH) were recruited. The patients were split into 3 different groups based on the hematoma size: group 1:volume<10 ml(n=89), group 2: volume between 10 and 20 ml (n=59), and group 3:volume>20 ml(n=50). And the shape of the hematoma was classed into regular (round to ellipsoid) with smooth margins (n=76), irregular with frayed margins (n=85), and multilobular (n=37). The slice method, voxelization method, and 3D-Slicer method were adopted to measure the volume of hematoma, respectively, considering the nonclosed models and the models which may contain inaccurate normal information during CT scan. Moreover, the results were compared with the 3D-Slicer method for closed models.Results. There was a significant estimation error (P<0.05) using these three methods to calculate the volume of the closed hematoma model. The estimated hematoma volume was calculated to be14.2086743 +/- 0.900559087 ml,14.2119130 +/- 0.900851812 ml, and14.2123825 +/- 0.900835916 ml using slice method 1, slice method 2, and the voxelization method, respectively, compared to14.212656 +/- 0.900992371 ml using the 3D-Slicer method. The mean estimation error was-0.00398172 ml,-0.00074303 ml, and-0.00027354 ml caused by slice method 1, slice method 2, and voxelization method, respectively. There was a significant estimation error (P<0.05), applying these three methods to calculate the volume of the nonclosed hematoma model. The estimated hematoma volume was calculated to be14.1928246 +/- 0.902210314 ml using the 3D-Slicer method. The mean estimation error was calculated to be-0.00402121 ml,-0.00078237 ml, -0.00031288 ml, and-0.01983136 ml using slice method 1, slice method 2, voxelization method, and 3D-Slicer method, respectively.Conclusions. The 3D-Slicer software method is considered as a stable and capable method of high precision for the calculation of a closed hematoma model with correct normal direction, while it would be inappropriate for the nonclosed model nor the model with incorrect normal direction. The slice method and voxelization method can be the supplement and improvement of the 3D-Slicer software method, for the purpose of achieving precision medicine.

SCI ; EI

英语

其他

National Natural Science Foundation of China[11671009][11801513] ; Zhejiang Provincial Natural Science Foundation of China[LZ19A010002][LQ18A010008]

Mathematical & Computational Biology

Mathematical & Computational Biology

WOS:000556308600001

HINDAWI LTD

20214511126821

Computerized tomography ; Errors ; Patient monitoring ; Volume measurement

Biological Materials and Tissue Engineering:461.2 ; Medicine and Pharmacology:461.6 ; Computer Applications:723.5 ; Mechanical Variables Measurements:943.2

Web of Science

1.Zhejiang Sci Tech Univ, Coll Sci, Hangzhou 310018, Zhejiang, Peoples R China
2.Hangzhou Normal Univ, Affiliated Hosp, Hangzhou 310015, Zhejiang, Peoples R China
3.Southern Univ Sci & Technol, Coll Sci, Shenzhen 518055, Guangdong, Peoples R China

Chen, Minhong,Li, Zhong,Ding, Jianping,et al. Comparison of Common Methods for Precision Volume Measurement of Hematoma[J]. Computational and Mathematical Methods in Medicine,2020,2020.

Chen, Minhong,Li, Zhong,Ding, Jianping,Lu, Xingqi,Cheng, Yinan,&Lin, Jiayun.(2020).Comparison of Common Methods for Precision Volume Measurement of Hematoma.Computational and Mathematical Methods in Medicine,2020.

Chen, Minhong,et al."Comparison of Common Methods for Precision Volume Measurement of Hematoma".Computational and Mathematical Methods in Medicine 2020(2020).