南方科技大学知识苑(SUSTech KC): Drug-coated balloon versus drug-eluting stent for treating de novo coronary lesions in large vessels: a meta-analysis of clinical trials

题名	Drug-coated balloon versus drug-eluting stent for treating de novo coronary lesions in large vessels: a meta-analysis of clinical trials
作者	Lin, Yaowang; Sun, Xin; Liu, Huadong; Pang, Xinli; Dong, Shaohong
通讯作者	Dong, Shaohong
发表日期	2020-05-28
DOI	10.1007/s00059-020-04938-8
发表期刊	HERZ 影响因子和分区
ISSN	0340-9937
EISSN	1615-6692
摘要	Background Studies examining the efficiency of drug-coated balloon (DCB) compared to drug-eluting stents (DES) for de novo lesions in large vessels have reported inconsistent results. Objective This comprehensive meta-analysis of clinical trials compared the efficacy and safety of DCB and DES for the treatment of de novo coronary lesions. Methods The authors formally searched electronic databases before October 2019 to identify randomized and non-randomized clinical trials (RCTs and non-RCTs, respectively). Clinical trials were eligible for inclusion if they compared DCB with DES in patients with coronary lumen diameters >2.5 & x202f;mm. Results Three RCTs and one non-RCT with a total of 321 patients were included in our meta-analysis (DCB group & x202f;= 152, DES group & x202f;= 169). The primary endpoint was in-segment late lumen loss (LLL) with a standardized mean difference (SMD) of -0.07 (95% confidence interval [CI]: -0.31, 0.316;P & x202f;= 0.548) and the secondary endpoint was target lesion revascularization (TLR) with a risk ratio (RR) of 1.17 (95% CI: 0.46, 2.95;P & x202f;= 0.746). Conclusion This meta-analysis indicated that DCB might be non-inferior to DES as evidenced by quantitative coronary angiography (QCA) assessed at 6-9 months after percutaneous coronary intervention in patients presenting with coronary artery disease.
关键词	Percutaneous coronary intervention Coronary stenosis DCB DES De novo lesion
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	Shenzhen Municipal Health Commission[SZFZ2017029]
WOS研究方向	Cardiovascular System & Cardiology
WOS类目	Cardiac & Cardiovascular Systems
WOS记录号	WOS:000559609700002
出版者	URBAN & VOGEL
ESI学科分类	CLINICAL MEDICINE
来源库	Web of Science
引用统计	被引频次[WOS]：14
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/186792
专题	南方科技大学第一附属医院
作者单位	South Univ Sci & Technol, Jinan Univ, Affiliated Hosp 1, Dept Cardiol,Shenzhen Peoples Hosp,Clin Med Coll, 1017 Dongmen Northern Rd, Shenzhen 518020, Peoples R China
第一作者单位	南方科技大学第一附属医院
通讯作者单位	南方科技大学第一附属医院
第一作者的第一单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Lin, Yaowang,Sun, Xin,Liu, Huadong,et al. Drug-coated balloon versus drug-eluting stent for treating de novo coronary lesions in large vessels: a meta-analysis of clinical trials[J]. HERZ,2020.
APA	Lin, Yaowang,Sun, Xin,Liu, Huadong,Pang, Xinli,&Dong, Shaohong.(2020).Drug-coated balloon versus drug-eluting stent for treating de novo coronary lesions in large vessels: a meta-analysis of clinical trials.HERZ.
MLA	Lin, Yaowang,et al."Drug-coated balloon versus drug-eluting stent for treating de novo coronary lesions in large vessels: a meta-analysis of clinical trials".HERZ (2020).