The Time Sequences of Respiratory and Rectal Viral Shedding in Patients With Coronavirus Disease 2019

Zhao, Fang1; Yang, Yang1; Wang, Zhaoqin1; Li, Liang2; Liu, Lei1; Liu, Yingxia1

2020-09

10.1053/j.gastro.2020.05.035

GASTROENTEROLOGY   影响因子和分区

0016-5085

1528-0012

Recent studies have found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be detected in fecal samples and that the live virus could be successfully isolated from stool and used for successful infection in cell cultures, indicating a possible fecal-oral transmission.1-3 Although important for disease management, information on the time sequences of oral and fecal viral shedding in patients with coronavirus disease 2019 (COVID-19) needs more investigation.1,4 In this study, we tested in 401 patients with COVID-19 for viral RNA in both respiratory and rectal specimens and tracked them for more than 7 weeks to present a clear elucidation of the respiratory and rectal viral shedding profile, such as the duration, viral load, and relationship to patient symptoms.

Severe Acute Respiratory Syndrome Coronavirus 2 Coronavirus Disease 2019 Profile of Viral Shedding Gastroin-testinal Viral Reservoir

SCI

英语

第一 ; 通讯

Ministry of Science and Technology[2020YFC0846300] ; National Natural Science Foundation of China[2018ZX10711001][2017ZX10103011][2017ZX10204401] ; Shenzhen Science and Technology Innovation Commission for Research and Development Project[JCYJ20180228162201541][202002073000001] ; Sanming Project of Medicine in Shenzhen[SZSM201412003][SZSM201512005] ; China Postdoctoral Science Foundation[2019T120147][2019M660836]

Gastroenterology & Hepatology

Gastroenterology & Hepatology

WOS:000573218700015

W B SAUNDERS CO-ELSEVIER INC

CLINICAL MEDICINE

Web of Science

1.Southern Univ Sci & Technol, Natl Clin Res Ctr Infect Dis, State Key Discipline Infect Dis, Dept Infect Dis,Shenzhen Peoples Hosp 3,Hosp 2, Shenzhen, Guangdong, Peoples R China
2.Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Guangdong, Peoples R China

Zhao, Fang,Yang, Yang,Wang, Zhaoqin,et al. The Time Sequences of Respiratory and Rectal Viral Shedding in Patients With Coronavirus Disease 2019[J]. GASTROENTEROLOGY,2020,159(3):1158-+.

Zhao, Fang,Yang, Yang,Wang, Zhaoqin,Li, Liang,Liu, Lei,&Liu, Yingxia.(2020).The Time Sequences of Respiratory and Rectal Viral Shedding in Patients With Coronavirus Disease 2019.GASTROENTEROLOGY,159(3),1158-+.

Zhao, Fang,et al."The Time Sequences of Respiratory and Rectal Viral Shedding in Patients With Coronavirus Disease 2019".GASTROENTEROLOGY 159.3(2020):1158-+.