| 题名 | Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diary! Ketones by a Ru-Catalyst of Minimal Stereogenicity |
| 作者 | |
| 通讯作者 | Zhou，Min Jie; Xing，Xiangyou |
| 共同第一作者 | He，Dongxu; Xu，Xingjun |
| 发表日期 | 2020-11-06
|
| DOI | |
| 发表期刊 | |
| ISSN | 1523-7060
|
| EISSN | 1523-7052
|
| 卷号 | 22期号:21页码:8458-8463 |
| 摘要 | A highly enantioselective asymmetric transfer hydrogenation (ATH) of densely functionalized diheteroaryl and diaryl ketones was developed using Ru-catalysts of minimal stereogenicity. Various ketone substrates with structurally and electronically similar groups attached to the prochiral centers were reduced successfully in good to excellent enantioselectivities and yields. This protocol provides practical and efficient access to chiral diheteroarylmethanols and benzhydrols, which are key intermediates in pharmaceuticals and biologically active compounds. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | NI期刊
|
| 学校署名 | 第一
; 共同第一
; 通讯
|
| 资助项目 | Shenzhen Nobel Prize Scientists Laboratory Projectand Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Organic
|
| WOS记录号 | WOS:000589942900052
|
| 出版者 | |
| ESI学科分类 | CHEMISTRY
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：19
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/209257 |
| 专题 | 理学院_化学系 深圳格拉布斯研究院 |
| 作者单位 | 1.Shenzhen Grubbs Institute and Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China 2.College of Chemistry and Molecular Sciences,Wuhan University,Wuhan, Hubei,430072,China |
| 第一作者单位 | 化学系; 深圳格拉布斯研究院 |
| 通讯作者单位 | 化学系; 深圳格拉布斯研究院 |
| 第一作者的第一单位 | 化学系; 深圳格拉布斯研究院 |
| 推荐引用方式 GB/T 7714 |
He，Dongxu,Xu，Xingjun,Lu，Yi,et al. Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diary! Ketones by a Ru-Catalyst of Minimal Stereogenicity[J]. ORGANIC LETTERS,2020,22(21):8458-8463.
|
| APA |
He，Dongxu,Xu，Xingjun,Lu，Yi,Zhou，Min Jie,&Xing，Xiangyou.(2020).Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diary! Ketones by a Ru-Catalyst of Minimal Stereogenicity.ORGANIC LETTERS,22(21),8458-8463.
|
| MLA |
He，Dongxu,et al."Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diary! Ketones by a Ru-Catalyst of Minimal Stereogenicity".ORGANIC LETTERS 22.21(2020):8458-8463.
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| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | 操作 | |
| 4-acs.orglett.0c0306（1647KB） | -- | -- | 限制开放 | -- | ||
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