Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives

Ali，Muhammad Ubaid1; Lin，Siyi1,2; Yousaf，Balal3,4; Abbas，Qumber3; Munir，Mehr Ahmed Mujtaba3; Rashid，Audil5; Zheng，Chunmiao1; Kuang，Xingxing1; Wong，Ming Hung1,6

2020

10.1080/10643389.2020.1831359

CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY   影响因子和分区

1064-3389

1547-6537

Ultrafine particles (UFPs) with an aerodynamic diameter of <0.1 µm are emerging as the most dominant and abundant particulate matter. Human exposure to these particles has increased dramatically, especially in the indoor environment as most of the population spend 80 to 90% time in the indoor environment. Due to the small size, it is believed that these particles will impose more dangerous and aggressive health impacts. However, knowledge of UFPs is still lacking as most of the previous studies focused on PM and PM. The current article aims to provide a critical overview of UFPs sources, composition, physicochemical properties, potential exposure route, toxicity mechanisms, and health impacts to identify the research gaps and future research directions and perspectives. It is commonly observed that inhalation is the dominant route of exposure. Inhaled ultra-fine particles can penetrate deep into the respiratory track, resulting in adverse health impacts, ranging from normal transient of respiratory problems to cardiovascular and respiratory mortality and morbidity, lung cancer, brain disease, mutagenic and carcinogenic impacts. Due to the large surface area, these particles can transport a variety of toxins causing tissue and cell injury, leading to enhanced oxidative stress and inflammation. In order to overcome the environmental burden and health consequences attributed to ultrafine particles, proper air quality guidelines should be introduced and it is suggested that future research should focus on the relationship between health symptoms and UFPs physicochemical properties, especially the mechanics of chemical transformation in human body, their biological behavior, and toxicological effect.

Air pollution: indoor air quality physio-chemical properties ultra-fine particles

SCI ; EI

英语

第一 ; 通讯

Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control[2017B030301012] ; National Natural Science Foundation of China[41890852]

Environmental Sciences & Ecology

Environmental Sciences

WOS:000577346000001

TAYLOR & FRANCIS INC

20204209354747

Toxicity ; Air quality ; Diseases ; Indoor air pollution

Air Pollution:451 ; Air Pollution Control:451.2 ; Health Care:461.7 ; Physical Chemistry:801.4

ENVIRONMENT/ECOLOGY

2-s2.0-85092453573

Scopus

1.Guangdong Provincial Key Laboratory of Soil and Groundwater Pollution Control,and State Environmental Protection Key Laboratory of Integrated Surface Water-Groundwater Pollution Control,School of Environmental Science and Engineering,Southern University of Science and Technology,Shenzhen,China
2.Department of Chemistry,Hong Kong Baptist University,Hong Kong
3.CAS-Key Laboratory of Crust-Mantle Materials and the Environments,School of Earth and Space Sciences,University of Science and Technology of China,Hefei,China
4.Department of Environment Engineering,Middle East Technical University,,Turkey,Ankara,Turkey
5.Department of Botany,Faculty of Science,University of Gujrat,Gujrat,Pakistan
6.Consortium on Health,Environment,Education and Research (CHEER),Department of Science and Environmental Studies,The Education University of Hong Kong,Hong Kong

Ali，Muhammad Ubaid,Lin，Siyi,Yousaf，Balal,et al. Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives[J]. CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY,2020,52(3):436-473.

Ali，Muhammad Ubaid.,Lin，Siyi.,Yousaf，Balal.,Abbas，Qumber.,Munir，Mehr Ahmed Mujtaba.,...&Wong，Ming Hung.(2020).Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives.CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY,52(3),436-473.

Ali，Muhammad Ubaid,et al."Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives".CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY 52.3(2020):436-473.