南方科技大学知识苑(SUSTech KC): C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model

题名	C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model
作者	Zeng，Liyao 1,2; Yang，Huaxin1 ; Zhao，Menglong 1; Wen，Jialin1,3 ; Tucker，James H.R.2; Zhang，Xumu1
通讯作者	Wen，Jialin; Zhang，Xumu
发表日期	2020-12-04
DOI	10.1021/acscatal.0c04206
发表期刊	ACS Catalysis 影响因子和分区
ISSN	2155-5435
卷号	10 期号:23页码:13794-13799
摘要	A family of ferrocene-based chiral PNP ligands is reported. These tridentate ligands were successfully applied in Mn- catalyzed asymmetric hydrogenation of ketones, giving high enantioselectivities (92%similar to 99% ee for aryl alkyl ketones) as well as high efficiencies (TON up to 2000). In additiondialkyl ketones could also be hydrogenated smoothly. Manganese intermediates that might be involved in the catalytic cycle were analyzed. DFT calculation was carried out to help understand the chiral induction model. The Mn/PNP catalyst could discriminate two groups with different steric properties by deformation of the phosphine moiety in the flexible 5-membered ring.
关键词	Pnp Ligand Manganese Asymmetric Hydrogenation Ketone Enantioinduction Model
相关链接	[来源记录]
收录类别	SCI ; EI
语种	英语
学校署名	第一 ; 通讯
资助项目	National Natural Science Foundation of China[21801118] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002] ; Science, Technology and Innovation Commission of Shenzhen[KQTD20150717103157174]
WOS研究方向	Chemistry
WOS类目	Chemistry, Physical
WOS记录号	WOS:000598140200003
出版者	AMER CHEMICAL SOC
来源库	Web of Science
引用统计	被引频次[WOS]：57
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/209571
专题	理学院_化学系前沿与交叉科学研究院深圳格拉布斯研究院
作者单位	1.Shenzhen Grubbs Institute,Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Road,518055,China 2.School of Chemistry,University of Birmingham,Edgbaston, Birmingham,B15 2TT,United Kingdom 3.Academy for Advanced Interdisciplinary Studies,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Road,518055,China
第一作者单位	化学系; 深圳格拉布斯研究院
通讯作者单位	化学系; 深圳格拉布斯研究院; 前沿与交叉科学研究院
第一作者的第一单位	化学系; 深圳格拉布斯研究院
推荐引用方式 GB/T 7714	Zeng，Liyao,Yang，Huaxin,Zhao，Menglong,et al. C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model[J]. ACS Catalysis,2020,10(23):13794-13799.
APA	Zeng，Liyao,Yang，Huaxin,Zhao，Menglong,Wen，Jialin,Tucker，James H.R.,&Zhang，Xumu.(2020).C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model.ACS Catalysis,10(23),13794-13799.
MLA	Zeng，Liyao,et al."C1-Symmetric PNP Ligands for Manganese-Catalyzed Enantioselective Hydrogenation of Ketones: Reaction Scope and Enantioinduction Model".ACS Catalysis 10.23(2020):13794-13799.