Case Report: Overlapping Multiple Sclerosis With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature

Huang，Ying; Wang，Qian; Zeng，Silin; Zhang，Yaqing; Zou，Liangyu; Fu，Xuejun; Xu，Qianhui

2020-12-09

10.3389/fimmu.2020.595417

Frontiers in Immunology   影响因子和分区

1664-3224

1664-3224

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder mediated by NMDAR antibodies, typically manifesting as behavioral complaints, psychosis, seizures, movement disorders, hypoventilation, and autonomic dysfunction. In recent years, the predisposing factors and pathophysiological mechanisms of anti-NMDAR encephalitis have been tried to be clarified. It has been recognized that an overlap may be observed between anti-NMDAR encephalitis and inflammatory demyelinating disease. However, anti-NMDAR encephalitis is rarely associated with multiple sclerosis. Here, we describe a Chinese female patient diagnosed with relapsing remitting multiple sclerosis who developed anti-NMDAR encephalitis. Further, we discuss the previously reported literature.

anti-NMDA antibody anti-NMDA receptor encephalitis atypical symptoms multiple sclerosis overlap

SCI

英语

第一 ; 通讯

Immunology

Immunology

WOS:000600941300001

FRONTIERS MEDIA SA

2-s2.0-85098179826

Scopus

Department of Neurology,Shenzhen People’s Hospital,The Second Clinical Medical College,Jinan University,The First Affiliated Hospital,Southern University of Science and Technology),Shenzhen,China

Huang，Ying,Wang，Qian,Zeng，Silin,et al. Case Report: Overlapping Multiple Sclerosis With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature[J]. Frontiers in Immunology,2020,11.

Huang，Ying.,Wang，Qian.,Zeng，Silin.,Zhang，Yaqing.,Zou，Liangyu.,...&Xu，Qianhui.(2020).Case Report: Overlapping Multiple Sclerosis With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature.Frontiers in Immunology,11.

Huang，Ying,et al."Case Report: Overlapping Multiple Sclerosis With Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report and Review of Literature".Frontiers in Immunology 11(2020).