题名 | T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation |
作者 | |
通讯作者 | Yang, Liang |
发表日期 | 2021
|
DOI | |
发表期刊 | |
EISSN | 1422-0067
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卷号 | 22期号:2 |
摘要 | The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to compete with the host and to coordinate the invasion process. The T6SS apparatus consists of a membrane complex and an inner tail tube-like structure that is surrounded by a contractile sheath and capped with a spike complex. A series of antibacterial or antieukaryotic effectors is delivered by the puncturing device consisting of a Hcp tube decorated by the VgrG/PAAR complex into the target following the contraction of the TssB/C sheath, which often leads to damage and death of the competitor and/or host cells. As a tool for protein secretion and interspecies interactions, T6SS can be triggered by many different mechanisms to respond to various physiological conditions. This review summarizes our current knowledge of T6SS in coordinating bacterial stress responses against the unfavorable environmental and host conditions. |
关键词 | |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
|
学校署名 | 第一
; 通讯
|
资助项目 | Guangdong Natural Science Foundation for Distinguished Young Scholar[2020B1515020003]
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WOS研究方向 | Biochemistry & Molecular Biology
; Chemistry
|
WOS类目 | Biochemistry & Molecular Biology
; Chemistry, Multidisciplinary
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WOS记录号 | WOS:000611319300001
|
出版者 | |
ESI学科分类 | CHEMISTRY
|
来源库 | Web of Science
|
引用统计 |
被引频次[WOS]:34
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成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/215707 |
专题 | 南方科技大学医学院 |
作者单位 | Southern Univ Sci & Technol, Sch Med, Shenzhen 518055, Peoples R China |
第一作者单位 | 南方科技大学医学院 |
通讯作者单位 | 南方科技大学医学院 |
第一作者的第一单位 | 南方科技大学医学院 |
推荐引用方式 GB/T 7714 |
Yu, Kai-Wei,Xue, Peng,Fu, Yang,et al. T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021,22(2).
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APA |
Yu, Kai-Wei,Xue, Peng,Fu, Yang,&Yang, Liang.(2021).T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,22(2).
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MLA |
Yu, Kai-Wei,et al."T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22.2(2021).
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条目包含的文件 | 条目无相关文件。 |
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