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题名

T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation

作者
通讯作者Yang, Liang
发表日期
2021
DOI
发表期刊
EISSN
1422-0067
卷号22期号:2
摘要
The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to compete with the host and to coordinate the invasion process. The T6SS apparatus consists of a membrane complex and an inner tail tube-like structure that is surrounded by a contractile sheath and capped with a spike complex. A series of antibacterial or antieukaryotic effectors is delivered by the puncturing device consisting of a Hcp tube decorated by the VgrG/PAAR complex into the target following the contraction of the TssB/C sheath, which often leads to damage and death of the competitor and/or host cells. As a tool for protein secretion and interspecies interactions, T6SS can be triggered by many different mechanisms to respond to various physiological conditions. This review summarizes our current knowledge of T6SS in coordinating bacterial stress responses against the unfavorable environmental and host conditions.
关键词
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语种
英语
学校署名
第一 ; 通讯
资助项目
Guangdong Natural Science Foundation for Distinguished Young Scholar[2020B1515020003]
WOS研究方向
Biochemistry & Molecular Biology ; Chemistry
WOS类目
Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号
WOS:000611319300001
出版者
ESI学科分类
CHEMISTRY
来源库
Web of Science
引用统计
被引频次[WOS]:34
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/215707
专题南方科技大学医学院
作者单位
Southern Univ Sci & Technol, Sch Med, Shenzhen 518055, Peoples R China
第一作者单位南方科技大学医学院
通讯作者单位南方科技大学医学院
第一作者的第一单位南方科技大学医学院
推荐引用方式
GB/T 7714
Yu, Kai-Wei,Xue, Peng,Fu, Yang,et al. T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021,22(2).
APA
Yu, Kai-Wei,Xue, Peng,Fu, Yang,&Yang, Liang.(2021).T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,22(2).
MLA
Yu, Kai-Wei,et al."T6SS Mediated Stress Responses for Bacterial Environmental Survival and Host Adaptation".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22.2(2021).
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