Recent advances in semiconducting polymer dots as optical probes for biosensing

Yuan, Ye1; Hou, Weiying2; Qin, Weiping1; Wu, Changfeng2

2021-01-21

10.1039/d0bm01038c

Biomaterials Science   影响因子和分区

2047-4830

2047-4849

Optical probes that specifically and sensitively change the optical properties upon contact with targets have become irreplaceable tools in fundamental biology and medicine. Semiconducting polymer dots (Pdots) have emerged as popular optical nanoplatforms because of their excellent characteristics, such as tunable luminescence, high brightness, superior stability and biocompatibility, for biological applications. In particular, facile surface and intra-particle modifications enable Pdots to detect various biological parameters, such as reactive oxygen species (ROS), typical metal ions, pH values, temperature and a variety of biomolecules. In this review, we provide a brief overview of the preparation and bio-functionalization strategies of Pdots. This review focuses on the applications of Pdots as optical probes in biosensors and describes the challenges in this field.

SCI ; EI

英语

通讯

Shenzhen Science and Technology Innovation Commission[KQTD20170810111314625] ; National Natural Science Foundation of China[81771930] ; National Key Research and Development Program of China[2018YFB0407200]

Materials Science

Materials Science, Biomaterials

WOS:000611729300005

ROYAL SOC CHEMISTRY

20210609878738

Biocompatibility ; Metal ions ; Metals ; Molecular biology ; Probes

Biology:461.9 ; Immunology:461.9.1 ; Metallurgy:531.1 ; Light/Optics:741.1

Web of Science

1.Jilin Univ, Coll Elect Sci & Engn, State Key Lab Integrated Optoelect, Changchun 130012, Jilin, Peoples R China
2.Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen 518055, Guangdong, Peoples R China

Yuan, Ye,Hou, Weiying,Qin, Weiping,et al. Recent advances in semiconducting polymer dots as optical probes for biosensing[J]. Biomaterials Science,2021,9(2):328-346.

Yuan, Ye,Hou, Weiying,Qin, Weiping,&Wu, Changfeng.(2021).Recent advances in semiconducting polymer dots as optical probes for biosensing.Biomaterials Science,9(2),328-346.

Yuan, Ye,et al."Recent advances in semiconducting polymer dots as optical probes for biosensing".Biomaterials Science 9.2(2021):328-346.