题名 | Optical resolution photoacoustic computed microscopy |
作者 | |
通讯作者 | Xi, Lei |
发表日期 | 2021-01-15
|
DOI | |
发表期刊 | |
ISSN | 0146-9592
|
EISSN | 1539-4794
|
卷号 | 46期号:2页码:372-375 |
摘要 | Optical resolution photoacoustic microscopy (ORPAM) has demonstrated both high resolution and rich contrast imaging of optical chromophores in biologic tissues. To date, sensitivity remains a major challenge for ORPAM, which limits the capability of resolving biologic microvascular networks. In this study, we propose and evaluate a new ORPAM modality termed as optical resolution photoacoustic computed microscopy (ORPACM), through the combination of a two-dimensional laser-scanning system with a medical ultrasonographic platform. Apart from conventional ORPAMs, we record multiple photoacoustic (PA) signals using a 128-element ultrasonic transducer array for each pulse excitation. Then, we apply a reconstruction algorithm to recover one depth-resolved PA signal referred to as an A-line, which reveals more detailed information compared with conventional single-element transducer-based ORPAMs. In addition, we carried out both in vitro and in vivo experiments as well as quantitative analyses to show the advanced features of ORPACM. (C) 2021 Optical Society of America |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
|
学校署名 | 第一
; 通讯
|
资助项目 | National Natural Science Foundation of China[62022037,61775028,81571722,61528401]
; Guangdong Science and Technology Department["2019ZT08Y191","SZBL2020090501013"]
; Science, Technology and Innovation Commission of Shenzhen Municipality[KQTD20190929172743294]
|
WOS研究方向 | Optics
|
WOS类目 | Optics
|
WOS记录号 | WOS:000608835900055
|
出版者 | |
EI入藏号 | 20211310131841
|
EI主题词 | Chromophores
; Transducers
; Ultrasonic transducers
|
EI分类号 | Imaging Techniques:746
; Ultrasonic Devices:753.2
; Organic Compounds:804.1
|
ESI学科分类 | PHYSICS
|
来源库 | Web of Science
|
引用统计 |
被引频次[WOS]:2
|
成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/221085 |
专题 | 工学院_生物医学工程系 |
作者单位 | 1.Southern Univ Sci & Technol, Dept Biomed Engn, Shenzhen 518055, Guangdong, Peoples R China 2.Chinese Acad Sci, Shenzhen Inst Adv Technol, Res Lab Biomed Opt & Mol Imaging, Shenzhen 518055, Guangdong, Peoples R China |
第一作者单位 | 生物医学工程系 |
通讯作者单位 | 生物医学工程系 |
第一作者的第一单位 | 生物医学工程系 |
推荐引用方式 GB/T 7714 |
Qi, Weizhi,Liang, Xiao,Ji, Yaoyao,et al. Optical resolution photoacoustic computed microscopy[J]. OPTICS LETTERS,2021,46(2):372-375.
|
APA |
Qi, Weizhi,Liang, Xiao,Ji, Yaoyao,Liu, Chengbo,&Xi, Lei.(2021).Optical resolution photoacoustic computed microscopy.OPTICS LETTERS,46(2),372-375.
|
MLA |
Qi, Weizhi,et al."Optical resolution photoacoustic computed microscopy".OPTICS LETTERS 46.2(2021):372-375.
|
条目包含的文件 | 条目无相关文件。 |
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