Point of Care Diagnostics in the Age of COVID-19

Rezaei, Meysam1,2,3; Razavi Bazaz, Sajad1,2; Zhand, Sareh1; Sayyadi, Nima1,4; Jin, Dayong2,3; Stewart, Martin P.2,5; Ebrahimi Warkiani, Majid1,2,3,6

2021

10.3390/diagnostics11010009

DIAGNOSTICS   影响因子和分区

2075-4418

The recent outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated serious respiratory disease, coronavirus disease 2019 (COVID-19), poses a major threat to global public health. Owing to the lack of vaccine and effective treatments, many countries have been overwhelmed with an exponential spread of the virus and surge in the number of confirmed COVID-19 cases. Current standard diagnostic methods are inadequate for widespread testing as they suffer from prolonged turn-around times (>12 h) and mostly rely on high-biosafety-level laboratories and well-trained technicians. Point-of-care (POC) tests have the potential to vastly improve healthcare in several ways, ranging from enabling earlier detection and easier monitoring of disease to reaching remote populations. In recent years, the field of POC diagnostics has improved markedly with the advent of micro- and nanotechnologies. Due to the COVID-19 pandemic, POC technologies have been rapidly innovated to address key limitations faced in existing standard diagnostic methods. This review summarizes and compares the latest available POC immunoassay, nucleic acid-based and clustered regularly interspaced short palindromic repeats- (CRISPR)-mediated tests for SARS-CoV-2 detection that we anticipate aiding healthcare facilities to control virus infection and prevent subsequent spread.

SARS-CoV-2 COVID-19 point of care testing respiratory diseases

SCI

英语

通讯

Australian Research Council["DP170103704","DP180103003","DP200101860"] ; National Health and Medical Research Council through the Career Development Fellowship[APP1143377] ; Australia-China Joint Research Centre for Point-of-Care Testing["ACSRF65827","SQ2017YFGH001190"] ; Science and Technology Innovation Commission of Shenzhen[KQTD20170810110913065]

General & Internal Medicine

Medicine, General & Internal

WOS:000610111200001

MDPI

Web of Science

1.Univ Technol Sydney, Sch Biomed Engn, Sydney, NSW 2007, Australia
2.Univ Technol Sydney, Fac Sci, Inst Biomed Mat & Devices IBMD, Sydney, NSW 2007, Australia
3.Southern Univ Sci & Technol, SUStech UTS Joint Res Ctr Biomed Mat & Devices, Shenzhen 518055, Peoples R China
4.Macquarie Univ Sydney, Fac Med & Hlth Sci, Dept Biomed Sci, Sydney, NSW 2109, Australia
5.Univ Technol Sydney, Fac Sci, Sch Life Sci, Sydney, NSW 2007, Australia
6.Sechenov Univ, Inst Mol Med, Moscow 119991, Russia

Rezaei, Meysam,Razavi Bazaz, Sajad,Zhand, Sareh,et al. Point of Care Diagnostics in the Age of COVID-19[J]. DIAGNOSTICS,2021,11(1).

Rezaei, Meysam.,Razavi Bazaz, Sajad.,Zhand, Sareh.,Sayyadi, Nima.,Jin, Dayong.,...&Ebrahimi Warkiani, Majid.(2021).Point of Care Diagnostics in the Age of COVID-19.DIAGNOSTICS,11(1).

Rezaei, Meysam,et al."Point of Care Diagnostics in the Age of COVID-19".DIAGNOSTICS 11.1(2021).