Assessment of the health utility of patients with leukemia in China

Zeng, Xueyun1; Sui, Mingjie1; Liu, Rui1; Qian, Xinyu2; Li, Wenfeng3; Zheng, Erwei4; Yang, Jinjin1; Li, Jinmei5; Huang, Weidong1; Yang, Hongbin6; Yu, Hongjuan3,7; Luo, Nan2

2021-02-27

10.1186/s12955-021-01711-1

HEALTH AND QUALITY OF LIFE OUTCOMES   影响因子和分区

1477-7525

Objectives This study aimed to assess the health utility of leukemia patients in China using the EQ-5D-5L, compare it with the population norms, and identify the potential factors associated with health utility. Methods A hospital based cross-sectional survey was conducted in three tertiary hospitals from July 2015 to February 2016. A total of 186 patients with leukemia completed the EQ-5D-5L and their health utility scores were calculated using the Chinese value set. EQ-5D-5L utility and dimensions scores of leukemia patients were compared with China's population norms using Kruskal-Wallis test and chi square test. Potential factors associated with health utility were identified using Tobit regression. Results The mean EQ-5D-5L utility scores of patients with leukemia, grouped by either gender or age, were significantly lower than those of the general population (p < 0.001). The same results were found for individual dimensions of EQ-5D-5L, where leukemia patients reported more health problems than the general population (p < 0.001). The utility score of leukemia patients was found to be significantly related to medical insurance, religious belief, comorbidities, social support and ECOG performance status. Conclusion This study indicated that leukemia patients have worse health status compared to the general population of China and that multiple factors affect the health utility of the patients. The utility scores reported in this study could be useful in future cost-utility analysis.

Leukemia Health utility EQ-5D-5L Cancer

SCI ; SSCI

英语

通讯

National Social Science Foundation of China[71974048,71503062] ; China Medical Board[CMB-19-308]

Health Care Sciences & Services

Health Care Sciences & Services ; Health Policy & Services

WOS:000622712300001

BMC

2-s2.0-85101939240

Web of Science

1.Harbin Med Univ, Sch Hlth Management, Harbin 150086, Peoples R China
2.Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117549, Singapore
3.Harbin Med Univ, Dept Hematol, Affiliated Hosp 1, Harbin 150001, Peoples R China
4.Harbin Med Univ, Affiliated Hosp 1, Harbin 150001, Peoples R China
5.Publ Hlth Educ & Informat Ctr Heilongjiang Prov, Harbin 150063, Peoples R China
6.Harbin Med Univ, Dept Med Oncol, Affiliated Hosp 3, Harbin 150081, Peoples R China
7.Southern Univ Sci & Technol Hosp, Shenzhen 518055, Peoples R China

Zeng, Xueyun,Sui, Mingjie,Liu, Rui,et al. Assessment of the health utility of patients with leukemia in China[J]. HEALTH AND QUALITY OF LIFE OUTCOMES,2021,19(1).

Zeng, Xueyun.,Sui, Mingjie.,Liu, Rui.,Qian, Xinyu.,Li, Wenfeng.,...&Luo, Nan.(2021).Assessment of the health utility of patients with leukemia in China.HEALTH AND QUALITY OF LIFE OUTCOMES,19(1).

Zeng, Xueyun,et al."Assessment of the health utility of patients with leukemia in China".HEALTH AND QUALITY OF LIFE OUTCOMES 19.1(2021).