Evaluation of tooth demineralization and interfacial bacterial penetration around resin composites containing surface pre-reacted glass-ionomer (S-PRG) filler

Zhou，Yuan1; Hiraishi，Noriko2; Shimada，Yasushi2,3; Wang，Guoqing4; Tagami，Junji2; Feng，Xiping1

2021

10.1016/j.dental.2021.02.009

DENTAL MATERIALS   影响因子和分区

0109-5641

Objective: To evaluate preventive effects of S-PRG-filled resin-composites on surrounding tooth demineralization and interfacial bacterial penetration. Methods: Cavities were prepared on enamel or dentin blocks and treated by BeautiBond Universal (Shofu) and filled by resin-composites containing S-PRG filler (Shofu) at 0 wt% (P0, control), 10 wt% (P10), 30 wt% (P30), 50 wt% (P50) or 70 wt% (P70). The specimens were demineralized by Streptococcus mutans biofilms for 12 days. Wall lesion depth (WL-depth) and outer lesion depth (OL-depth) were measured from fluorescence microscopy. Interfacial bacterial penetration area (BPA) was evaluated from confocal laser scanning microscopy. Wall lesion hardness (WL-hardness) and outer lesion hardness (OL-hardness) were measured with a Vickers microhardness tester. Elemental analysis of resins and surrounding lesions was conducted by scanning electron microscopy and energy dispersive X-ray spectrometry. Results: Resin-composites in P70 contained significantly more F, Na and Al than that in P0 and P10. P70, P50 and P30 showed significantly lower WL-depth than P0. P70 showed significantly lower OL-depth, fewer Ca and P loss in lesions than P0. P70 showed significantly higher WL-hardness and OL-hardness in dentin specimens than P0. Enamel margins had a higher gap frequency than dentin margins. However, BPA did not show significant differences among the groups. Significance: Resin-composites containing S-PRG fillers at ≥30 wt% can inhibit wall lesions and that at 70 wt% can further decrease outer lesions, reduce Ca and P loss in lesions and increase surrounding dentin hardness. However, S-PRG-filled resin-composites does not inhibit interfacial biofilm penetration after a short-term demineralization period.

Bacterial penetration Microhardness Resin composites S-PRG filler Secondary caries SEM/EDS

SCI ; EI

英语

其他

WOS:000641025300010

20211010025899

Biofilms ; Enamels ; Fillers ; Fluorescence microscopy ; Hardness ; Scanning electron microscopy

Biomaterials (including synthetics):462.5 ; Coating Materials:813.2 ; Organic Polymers:815.1.1 ; Quantum Theory; Quantum Mechanics:931.4 ; Materials Science:951

CLINICAL MEDICINE

2-s2.0-85101877442

Scopus

1.Laboratory of Molecular and Preventive Dentistry,Department of Preventive Dentistry,Shanghai Ninth People's Hospital,Shanghai JiaoTong University School of Medicine,Shanghai,639 Zhizaoju Road, Huangpu District,200011,China
2.Department of Cariology and Operative Dentistry,Graduate School of Medical and Dental Sciences,Tokyo Medical and Dental University,Tokyo,1-5-45 Yushima, Bunkyo-ku,113-8549,Japan
3.Department of Operative Dentistry,Graduate School of Medicine,Dentistry and Pharmaceutical Sciences,Okayama University,Okayama,2-5-1 Shikata-cho, Kita-ku,700-8525,Japan
4.Department of Electrical and Electronic Engineering,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Ave, Nanshan District,518055,China

Zhou，Yuan,Hiraishi，Noriko,Shimada，Yasushi,et al. Evaluation of tooth demineralization and interfacial bacterial penetration around resin composites containing surface pre-reacted glass-ionomer (S-PRG) filler[J]. DENTAL MATERIALS,2021,37:849-862.

Zhou，Yuan,Hiraishi，Noriko,Shimada，Yasushi,Wang，Guoqing,Tagami，Junji,&Feng，Xiping.(2021).Evaluation of tooth demineralization and interfacial bacterial penetration around resin composites containing surface pre-reacted glass-ionomer (S-PRG) filler.DENTAL MATERIALS,37,849-862.

Zhou，Yuan,et al."Evaluation of tooth demineralization and interfacial bacterial penetration around resin composites containing surface pre-reacted glass-ionomer (S-PRG) filler".DENTAL MATERIALS 37(2021):849-862.