A three-dimensional pinwheel-shaped paper-based microfluidic analytical device for fluorescence detection of multiple heavy metals in coastal waters by rational device design

Wang, Milan1,2; Song, Zhihua3; Jiang, Youwei4; Zhang, Xiaolin1,2; Wang, Lin1,2; Zhao, Hongyu1,2; Cui, Yutong1,2; Gu, Furong1,2; Wang, Yunhua2,5; Zheng, Guoxia1,2

2021-03-01

10.1007/s00216-021-03269-9

ANALYTICAL AND BIOANALYTICAL CHEMISTRY   影响因子和分区

1618-2642

1618-2650

Here, we present the rational design of a pinwheel-shaped three-dimensional microfluidic paper-based analytical device (3D-mu PAD) for specific, sensitive and multiplexed detection of heavy metals in coastal waters. A more homogeneous permeation of fluids along the chip than common design, even under unskilled performance, has been achieved by the elaborate chip design of the hydrostatic balancing inlet port and uniformly stressed reversible sealing. With the combination of ion imprinted polymer grafted CdTe quantum-dots and fluid accumulation pad, 4 metals (Cu2+, Cd2+, Pb2+, and Hg2+) in 1 analysis and 25-fold enrichment for each metal can be simultaneously performed within 20 min, with detection limits of 0.007-0.015 mu g/L. It has the ability to selectively recognize these 4 metals in mixtures and immunizing to interferences from components found in coastal waters, which provided results that were in agreement with values gained from atomic absorption. The inexpensive and portable nature as well as the highly sensitive and flexible performance of the new developed 3D-mu PAD could make it attractive as an on-site testing approach for marine environmental monitoring.

Paper-based microfluidics Three-dimensional Reversible sealing Fluidic dispersion Metal detection Coastal waters

SCI ; EI

英语

其他

National Natural Science Foundation of China[41476085] ; Major Scientific Project of Interscholastic Collaboration of Universities in Liaoning[JYT-dldxjc202001] ; Science and Technology Innovation Development Plan of Yantai[2020MSGY112] ; Dalian Science and Technology Innovation Fund[2019J12SN55]

Biochemistry & Molecular Biology ; Chemistry

Biochemical Research Methods ; Chemistry, Analytical

WOS:000631781600001

SPRINGER HEIDELBERG

20211310150501

Cadmium telluride ; Heavy metals ; II-VI semiconductors ; Microfluidics ; Semiconductor quantum dots ; Well testing

Metallurgy and Metallography:531 ; Microfluidics:632.5.1 ; Semiconductor Devices and Integrated Circuits:714.2 ; Chemistry:801 ; Chemical Products Generally:804

CHEMISTRY

Web of Science

1.Dalian Univ, Chem & Environm Engn Inst, Dalian 116622, Peoples R China
2.Dalian Univ, Environm Micro Total Anal Lab, Dalian 116622, Peoples R China
3.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China
4.Southern Univ Sci & Technol, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China
5.Dalian Univ, Med Sch, Dalian 116622, Peoples R China

Wang, Milan,Song, Zhihua,Jiang, Youwei,et al. A three-dimensional pinwheel-shaped paper-based microfluidic analytical device for fluorescence detection of multiple heavy metals in coastal waters by rational device design[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2021,413:3299-3313.

Wang, Milan.,Song, Zhihua.,Jiang, Youwei.,Zhang, Xiaolin.,Wang, Lin.,...&Zheng, Guoxia.(2021).A three-dimensional pinwheel-shaped paper-based microfluidic analytical device for fluorescence detection of multiple heavy metals in coastal waters by rational device design.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,413,3299-3313.

Wang, Milan,et al."A three-dimensional pinwheel-shaped paper-based microfluidic analytical device for fluorescence detection of multiple heavy metals in coastal waters by rational device design".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 413(2021):3299-3313.