Metal-free access to 3-allyl-2-alkoxychromanonesviaphosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols

Meng，Ling1,2; Chang，Xiaoyong1; Lin，Zhenyang2; Wang，Jun (Joelle)1,3

2021-03-28

10.1039/d1ob00215e

ORGANIC & BIOMOLECULAR CHEMISTRY   影响因子和分区

1477-0520

A metal-free access to 3-allyl-2-alkoxychromanones by PPh-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols is described. This reaction is performed under mild conditions and it shows good functional group tolerance, providing a series of functionalized chromanones in moderate to high yields with excellent diastereoselectivities. Deuterium-labeling experiments to probe a possible mechanism and scale-up reaction were also conducted.

SCI ; IC ; CCR ; EI

英语

第一

WOS:000635741400005

20211410178514

Carbonates

Chemical Reactions:802.2 ; Inorganic Compounds:804.2

CHEMISTRY

2-s2.0-85103516477

Scopus

1.Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China
2.Department of Chemistry,Hong Kong University of Science & Technology,Clear Water Bay,Kowloon,Hong Kong
3.Department of Chemistry,Hong Kong Baptist University,Kowloon,Hong Kong

Meng，Ling,Chang，Xiaoyong,Lin，Zhenyang,et al. Metal-free access to 3-allyl-2-alkoxychromanonesviaphosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2021,19(12):2663-2667.

Meng，Ling,Chang，Xiaoyong,Lin，Zhenyang,&Wang，Jun .(2021).Metal-free access to 3-allyl-2-alkoxychromanonesviaphosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols.ORGANIC & BIOMOLECULAR CHEMISTRY,19(12),2663-2667.

Meng，Ling,et al."Metal-free access to 3-allyl-2-alkoxychromanonesviaphosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols".ORGANIC & BIOMOLECULAR CHEMISTRY 19.12(2021):2663-2667.