南方科技大学知识苑(SUSTech KC): Organocatalytic Enantioselective Aza-Michael Addition of Arylamines to 7-Methide-7H-Indoles

题名	Organocatalytic Enantioselective Aza-Michael Addition of Arylamines to 7-Methide-7H-Indoles
作者	Li，Fushuai 1; Yang，Zhihong 1; Yang，Yanyan 3; Huang，Qiuhong 1; Chen，Xuling2 ; Li，Pengfei2 ; Dong，Mingxin 1; Li，Wenjun 1
通讯作者	Li，Pengfei; Dong，Mingxin; Li，Wenjun
发表日期	2021
DOI	10.1002/adsc.202100039
发表期刊	ADVANCED SYNTHESIS & CATALYSIS 影响因子和分区
ISSN	1615-4150
EISSN	1615-4169
卷号	363页码:2557-2561
摘要	A chiral phosphorus acid catalyzed enantioselective 1,4-conjugate addition of arylamines to in situ formed 7-methylene-7H-indoles from 7-indolylmethanols has been developed for the first time. Without additives, the catalytic protocol enabled the formation of 1,4-adducts with a nitrogen-containing tertiary carbon stereocenter in 66–96% yield with 70–89% ee under mild conditions. (Figure presented.).
关键词	7-methylene-7h-indoles Arylamines Michael Addition Organocatalytic
相关链接	[Scopus记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	Special Funds of the Taishan Scholar Program of Shandong Province[tsqn201812047] ; Natural Science Foundation of Shandong Province[ZR2017JL011] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
WOS研究方向	Chemistry
WOS类目	Chemistry, Applied ; Chemistry, Organic
WOS记录号	WOS:000630392500001
出版者	WILEY-V C H VERLAG GMBH
Scopus记录号	2-s2.0-85103016767
来源库	Scopus
引用统计	被引频次[WOS]：12
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/222788
专题	理学院_化学系深圳格拉布斯研究院
作者单位	1.Department of Medicinal Chemistry,School of Pharmacy,Qingdao University,Qingdao,Shandong,266021,China 2.Shenzhen Grubbs Institute and Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen,518055,China 3.Department of Immunology,School of Basic Medicine,Qingdao University,Qingdao,266021,China
通讯作者单位	化学系; 深圳格拉布斯研究院
推荐引用方式 GB/T 7714	Li，Fushuai,Yang，Zhihong,Yang，Yanyan,et al. Organocatalytic Enantioselective Aza-Michael Addition of Arylamines to 7-Methide-7H-Indoles[J]. ADVANCED SYNTHESIS & CATALYSIS,2021,363:2557-2561.
APA	Li，Fushuai.,Yang，Zhihong.,Yang，Yanyan.,Huang，Qiuhong.,Chen，Xuling.,...&Li，Wenjun.(2021).Organocatalytic Enantioselective Aza-Michael Addition of Arylamines to 7-Methide-7H-Indoles.ADVANCED SYNTHESIS & CATALYSIS,363,2557-2561.
MLA	Li，Fushuai,et al."Organocatalytic Enantioselective Aza-Michael Addition of Arylamines to 7-Methide-7H-Indoles".ADVANCED SYNTHESIS & CATALYSIS 363(2021):2557-2561.