中文版 | English
题名

Axial localization and tracking of self-interference nanoparticles by lateral point spread functions

作者
通讯作者Wang,Fan; Jin,Dayong
发表日期
2021-12-01
DOI
发表期刊
ISSN
2041-1723
EISSN
2041-1723
卷号12期号:1
摘要

Sub-diffraction limited localization of fluorescent emitters is a key goal of microscopy imaging. Here, we report that single upconversion nanoparticles, containing multiple emission centres with random orientations, can generate a series of unique, bright and position-sensitive patterns in the spatial domain when placed on top of a mirror. Supported by our numerical simulation, we attribute this effect to the sum of each single emitter’s interference with its own mirror image. As a result, this configuration generates a series of sophisticated far-field point spread functions (PSFs), e.g. in Gaussian, doughnut and archery target shapes, strongly dependent on the phase difference between the emitter and its image. In this way, the axial locations of nanoparticles are transferred into far-field patterns. We demonstrate a real-time distance sensing technology with a localization accuracy of 2.8 nm, according to the atomic force microscope (AFM) characterization values, smaller than 1/350 of the excitation wavelength.

相关链接[Scopus记录]
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语种
英语
重要成果
NI论文
学校署名
通讯
资助项目
Australian Research Council[DP190101058] ; Australia-China Joint Research Centre for Point-of-Care Testing[
WOS研究方向
Science & Technology - Other Topics
WOS类目
Multidisciplinary Sciences
WOS记录号
WOS:000636772600006
出版者
Scopus记录号
2-s2.0-85103805917
来源库
Scopus
引用统计
被引频次[WOS]:15
成果类型期刊论文
条目标识符http://sustech.caswiz.com/handle/2SGJ60CL/223719
专题工学院_生物医学工程系
作者单位
1.Institute for Biomedical Materials and Devices (IBMD),Faculty of Science,University of Technology Sydney,Sydney,2007,Australia
2.School of Electrical and Data Engineering,Faculty of Engineering and Information Technology,University of Technology Sydney,Ultimo,2007,Australia
3.AG Nanooptik,Institut für Physik & IRIS Adlershof,Humboldt Universität zu Berlin,Berlin,Newtonstraße 15,12489,Germany
4.JCMwave GmbH,Berlin,Bolivarallee 22,14050,Germany
5.Zuse Institute Berlin,Berlin,Takustraße 7,14195,Germany
6.School of Biomedical Engineering,Faculty of Science,University of Technology,Sydney,2007,Australia
7.Department of Biomedical Engineering,College of Engineering,Peking University,Beijing,100871,China
8.UTS-SUStech Joint Research Centre for Biomedical Materials & Devices,Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen,518055,China
9.School of Chemical Engineering,University of New South Wales (UNSW),Sydney,Sydney Campus,2052,Australia
10.School of Applied and Engineering Physics,Cornell University,Ithaca,14853,United States
通讯作者单位生物医学工程系
推荐引用方式
GB/T 7714
Liu,Yongtao,Zhou,Zhiguang,Wang,Fan,et al. Axial localization and tracking of self-interference nanoparticles by lateral point spread functions[J]. Nature Communications,2021,12(1).
APA
Liu,Yongtao.,Zhou,Zhiguang.,Wang,Fan.,Kewes,Günter.,Wen,Shihui.,...&Jin,Dayong.(2021).Axial localization and tracking of self-interference nanoparticles by lateral point spread functions.Nature Communications,12(1).
MLA
Liu,Yongtao,et al."Axial localization and tracking of self-interference nanoparticles by lateral point spread functions".Nature Communications 12.1(2021).
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