| 题名 | Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging dagger |
| 作者 | |
| 通讯作者 | Liang, Meng; Nie, Guohui |
| 发表日期 | 2021-03-01
|
| DOI | |
| 发表期刊 | |
| ISSN | 1359-7345
|
| EISSN | 1364-548X
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| 摘要 | We describe an intracellular enzyme-powered DNA circuit probe with a tunable amplifier for sensitive and selective detection of miRNA. This approach has been successfully applied for in situ miRNA-21 fluorescence imaging in live cells. Also, we used chemicals to elevate the APE1 expression level rendering a tunable amplification strength for more flexible imaging applications. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | NI论文
|
| 学校署名 | 其他
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| 资助项目 | National Key Research and Development Project["2020YFC1316900","2020YFC1316901"]
; National Natural Science Foundation of China[52003161,81970875]
; Natural Science Foundation of Guangdong Province[2019A1515011495]
; China Postdoctoral Science Foundation["2019TQ0211","2019TQ0213"]
; Shenzhen Science and Technology Innovation Committee["ZDSYS201707281114196","JCYJ201 80508152528735"]
; Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties[SZGSP010]
; National Science and Technology Major Project during the 13th Five-Year Plan Period[2019ZX09721001-007]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Multidisciplinary
|
| WOS记录号 | WOS:000631581900001
|
| 出版者 | |
| ESI学科分类 | CHEMISTRY
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：12
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/226005 |
| 专题 | 南方科技大学第二附属医院 南方科技大学第一附属医院 |
| 作者单位 | 1.Shenzhen Univ, Inst Translat Med, Shenzhen Peoples Hosp 2, Hlth Sci Ctr,Dept Otolaryngol,Affiliated Hosp 1, Shenzhen 518035, Peoples R China 2.Southern Univ Sci & Technol, Natl Clin Res Ctr Infect Dis, Affiliated Hosp 2, Shenzhen Peoples Hosp 3, Shenzhen 518112, Peoples R China 3.Beijing Univ Chem Technol, Coll Life Sci & Technol, Beijing 100029, Peoples R China |
| 推荐引用方式 GB/T 7714 |
Yu, Yingjie,Li, Lidan,Li, Guobao,et al. Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging dagger[J]. CHEMICAL COMMUNICATIONS,2021.
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| APA |
Yu, Yingjie.,Li, Lidan.,Li, Guobao.,Zhou, Xu.,Deng, Tingting.,...&Nie, Guohui.(2021).Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging dagger.CHEMICAL COMMUNICATIONS.
|
| MLA |
Yu, Yingjie,et al."Intracellular enzyme-powered DNA circuit with a tunable amplifier for miRNA imaging dagger".CHEMICAL COMMUNICATIONS (2021).
|
| 条目包含的文件 | 条目无相关文件。 | |||||
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