Linderaggrenolides A-N, Oxygen-Conjugated Sesquiterpenoid Dimers from the Roots of Lindera aggregata

Liu，Xin1; Fu，Jing1; Yang，Ji1; Huang，Ancheng C.2; Li，Run Feng1; Bai，Li Ping1; Liu，Liang1; Jiang，Zhi Hong1; Zhu，Guo Yuan1

2021-03-02

10.1021/acsomega.0c06349

ACS Omega   影响因子和分区

2470-1343

Linderaggrenolides A-N (1-14), 14 new lindenane sesquiterpenoid dimers with oxygen bridges were isolated from the roots of Lindera aggregata. Their structures were elucidated on the basis of comprehensive spectroscopic data analysis, with the absolute configurations established by empirical approaches, electronic circular dichroism calculations, and X-ray crystallography. Compounds 8 and 9 were found to exhibit significant transforming growth factor-β inhibitory activity, with IC50 values of 25.91 and 21.52 μM, respectively.

SCI

英语

其他

WOS:000626269800081

2-s2.0-85104361296

Scopus

1.State Key Laboratory of Quality Research in Chinese Medicine,Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease,Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology,999078,Macao
2.Institute of Plant and Food Science,Department of Biology,Southern University of Science and Technology,Shenzhen,518055,China

Liu，Xin,Fu，Jing,Yang，Ji,et al. Linderaggrenolides A-N, Oxygen-Conjugated Sesquiterpenoid Dimers from the Roots of Lindera aggregata[J]. ACS Omega,2021,6(8):5898-5909.

Liu，Xin.,Fu，Jing.,Yang，Ji.,Huang，Ancheng C..,Li，Run Feng.,...&Zhu，Guo Yuan.(2021).Linderaggrenolides A-N, Oxygen-Conjugated Sesquiterpenoid Dimers from the Roots of Lindera aggregata.ACS Omega,6(8),5898-5909.

Liu，Xin,et al."Linderaggrenolides A-N, Oxygen-Conjugated Sesquiterpenoid Dimers from the Roots of Lindera aggregata".ACS Omega 6.8(2021):5898-5909.