| 题名 | Biomaterial-based physical regulation of macrophage behaviour |
| 作者 | |
| 通讯作者 | Wang, Chunming |
| 发表日期 | 2021-03-01
|
| DOI | |
| 发表期刊 | |
| ISSN | 2050-750X
|
| EISSN | 2050-7518
|
| 卷号 | 9页码:3608-3621 |
| 摘要 | Macrophages play a critical role in regulating immune reactions induced by implanted biomaterials. They are highly plastic and in response to diverse stimuli in the microenvironment can exhibit a spectrum of phenotypes and functions. In addition to biochemical signals, the physical properties of biomaterials are becoming increasingly appreciated for their significant impact on macrophage behaviour, and the underlying mechanisms deserve more in-depth investigations. This review first summarises the effects of key physical cues - including stiffness, topography, physical confinement and applied force - on macrophage behaviour. Then, it reviews the current knowledge of cellular sensing and transduction of physical cues into intracellular signals. Finally, it discusses the major challenges in understanding mechanical regulation that could provide insights for biomaterial design. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 其他
|
| 资助项目 | Science and Technology Development Fund, Macau SAR["0018/2019/AFJ","0097/2019/A2"]
; National Natural Science Foundation of China[32022088]
|
| WOS研究方向 | Materials Science
|
| WOS类目 | Materials Science, Biomaterials
|
| WOS记录号 | WOS:000639582800001
|
| 出版者 | |
| EI入藏号 | 20212010347945
|
| EI主题词 | Topography
|
| EI分类号 | Immunology:461.9.1
; Materials Science:951
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：31
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/228162 |
| 专题 | 工学院_材料科学与工程系 |
| 作者单位 | 1.Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China 2.Southern Univ Sci & Technol, Dept Mat Sci & Engn, Shenzhen, Guangdong, Peoples R China 3.Nanjing Univ, Med Sch, State Key Lab Pharmaceut Biotechnol, Nanjing 210023, Jiangsu, Peoples R China 4.Nanjing Univ, Sch Life Sci, Nanjing 210023, Jiangsu, Peoples R China |
| 推荐引用方式 GB/T 7714 |
Zhou, Huiqun,Xue, Yizebang,Dong, Lei,et al. Biomaterial-based physical regulation of macrophage behaviour[J]. Journal of Materials Chemistry B,2021,9:3608-3621.
|
| APA |
Zhou, Huiqun,Xue, Yizebang,Dong, Lei,&Wang, Chunming.(2021).Biomaterial-based physical regulation of macrophage behaviour.Journal of Materials Chemistry B,9,3608-3621.
|
| MLA |
Zhou, Huiqun,et al."Biomaterial-based physical regulation of macrophage behaviour".Journal of Materials Chemistry B 9(2021):3608-3621.
|
| 条目包含的文件 | 条目无相关文件。 | |||||
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