Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China

Liang, Feng1; Wang, Xianfeng2; Shao, Jianbo3; Chen, Jun2; Liu, Lei4; Li, Hui3; Xu, Yi5; He, Liya5,6; Liang, Huiying1,6; Li, Kuanrong1; Gong, Sitang5,6; Xia, Huimin1,6

2021-04-17

10.1186/s12879-021-06037-3

BMC INFECTIOUS DISEASES   影响因子和分区

1471-2334

BackgroundCoronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission.MethodsA total of 71 age-matched pediatric IA and COVID-19 patient pairs were formed and their clinical data on admission were compared.ResultsFever, cough, nasal congestion and nausea/vomiting were the most common symptoms on admission for both infections but occurred less often in COVID-19. The IA patients were more likely to have lower-than-normal levels of lymphocyte count and percentage and to have higher-than-normal levels of activated partial thromboplastin time, prothrombin time, serum C-reactive protein, and serum procalcitonin, while the COVID-19 patients had higher odds of having lower-than-normal levels of neutrophil count and percentage.ConclusionsThis study suggests that influenza A is more symptomatic than COVID-19 for children and might be an overall more severe infection at the time of admission.

Coronavirus disease 2019 Influenza a Pediatrics Retrospective study

SCI

英语

其他

Infectious Diseases

Infectious Diseases

WOS:000641744500007

BMC

IMMUNOLOGY

Web of Science

1.Guangzhou Med Univ, Clin Data Ctr, Guangzhou Women & Childrens Med Ctr, Guangzhou 510623, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 2, Dept Pediat, Peoples Hosp Shenzhen 3, Shenzhen, Guangdong, Peoples R China
3.Wuhan Childrens Hosp, Dept Pediat, Wuhan 430000, Hubei, Peoples R China
4.Third Peoples Hosp Shenzhen, Dept Infect Dis, Shenzhen 518112, Guangdong, Peoples R China
5.Guangzhou Med Univ, Guangzhou Women & Childrens Med Ctr, Dept Pediat, Guangzhou, Guangdong, Peoples R China
6.Guangzhou Med Univ, Guangdong Prov Childrens Med Res Ctr, Guangzhou Women & Childrens Med Ctr, Guangzhou, Guangdong, Peoples R China

Liang, Feng,Wang, Xianfeng,Shao, Jianbo,et al. Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China[J]. BMC INFECTIOUS DISEASES,2021,21(1).

Liang, Feng.,Wang, Xianfeng.,Shao, Jianbo.,Chen, Jun.,Liu, Lei.,...&Xia, Huimin.(2021).Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China.BMC INFECTIOUS DISEASES,21(1).

Liang, Feng,et al."Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China".BMC INFECTIOUS DISEASES 21.1(2021).