Ocular Anatomical and Functional Characteristics in Anisometropic Chinese Children

Zhong，Yuanyuan2; Zeng，Li2; Chen，Zhi2; Yang，Jianlong2; Liu，Jiang1

2021-05-01

10.1097/OPX.0000000000001692

Optometry and vision science : official publication of the American Academy of Optometry   影响因子和分区

1538-9235

SIGNIFICANCE: This research found that anterior and posterior biometrics differ in many aspects between fellow eyes of anisometropic children. This might shed light on the mechanisms underlying the onset and progression of anisometropia and myopia. PURPOSE: This study aimed to investigate the ocular biometric parameters, peripheral refraction, and accommodative lag of fellow eyes in anisometropic children. METHODS: Anisometropic children were recruited. Axial length (AL), vitreous chamber depth (VCD), central corneal thickness, anterior chamber depth (ACD), lens thickness (LT), simulated K readings, central and peripheral refractive errors, and accommodative lag were measured in both eyes. The subfoveal choroidal thickness, average choroidal thickness, and choroid vessel density of the 6 × 6-mm macular area were measured by optical coherence tomography. RESULTS: Thirty-two children aged 11.1 ± 1.7 years were enrolled. The average degree of anisometropia was 2.49 ± 0.88 D. The AL, VCD, ACD, and simulated K reading values were significantly larger in the more myopic eyes, whereas the LT value was significantly smaller. Subfoveal choroidal thickness (P = .001) and average choroidal thickness (P = .02) were smaller in the more myopic eyes than in the contralateral eyes, whereas choroid vessel density (P = .03) was larger. The amount of anisometropia had a significant positive correlation with the difference in AL (r = 0.869, P < .001), VCD (r = 0.853, P < .001), and ACD (r = 0.591, P < .001) and a negative correlation with the difference in LT (r = -0.457, P = .009). CONCLUSIONS: Ocular biometrics differ in many aspects between the fellow eyes of anisometropic Chinese children, and the difference is correlated with the degree of anisometropia.

SCI ; EI

英语

其他

WOS:000656122600010

20212310469875

Optical tomography

Bioengineering and Biology:461 ; Optical Devices and Systems:741.3

CLINICAL MEDICINE

2-s2.0-85106554164

Scopus

1.Department of Computer Science and Engineering,Southern University of Science and Technology,Shenzhen,China
2.

Zhong，Yuanyuan,Zeng，Li,Chen，Zhi,et al. Ocular Anatomical and Functional Characteristics in Anisometropic Chinese Children[J]. Optometry and vision science : official publication of the American Academy of Optometry,2021,98(5):476-482.

Zhong，Yuanyuan,Zeng，Li,Chen，Zhi,Yang，Jianlong,&Liu，Jiang.(2021).Ocular Anatomical and Functional Characteristics in Anisometropic Chinese Children.Optometry and vision science : official publication of the American Academy of Optometry,98(5),476-482.

Zhong，Yuanyuan,et al."Ocular Anatomical and Functional Characteristics in Anisometropic Chinese Children".Optometry and vision science : official publication of the American Academy of Optometry 98.5(2021):476-482.