| 题名 | A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral Multidentate N, N, P-Ligand |
| 作者 | |
| 通讯作者 | Gu，Qiang Shuai; Liu，Xin Yuan |
| 共同第一作者 | Li，Zhuang; Cheng，Xian Yan |
| 发表日期 | 2021-07-26
|
| DOI | |
| 发表期刊 | |
| ISSN | 0276-7333
|
| EISSN | 1520-6041
|
| 卷号 | 40期号:14页码:2215–2219 |
| 摘要 | A cobalt-catalyzed enantioconvergent radical Negishi C(sp3)-C(sp2) cross-coupling of racemic benzyl chlorides with arylzinc reagents has been developed in good yield with moderate enantioselectivities. This strategy provides an expedient access toward a range of enantioenriched 1,1-diarylmethanes. Key to this discovery is the utilization of a chiral multidentate anionic N,N,P-ligand to strongly coordinate with the cobalt catalyst and tune its chiral environment, thus achieving the enantiocontrol over the highly reactive prochiral alkyl radical species. |
| 相关链接 | [Scopus记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 第一
; 共同第一
; 通讯
|
| 资助项目 | National Natural Science Foundation of China[21831002,22025103,22001109,22001111]
; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
; Guangdong Innovative Program[2019BT02Y335]
; Guangdong Basic and Applied Basic Research Foundation[2019A1515110822]
; Shenzhen Special Funds[JCYJ20200109141001789]
; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis[ZDSYS20190902093215877]
; SUSTech Special Fund for the Construction of High-Level Universities[G02216303]
; Special Funds for the Cultivation of Guangdong College Students' Scientific and Technological Innovation[pdjh2020b0524]
|
| WOS研究方向 | Chemistry
|
| WOS类目 | Chemistry, Inorganic & Nuclear
; Chemistry, Organic
|
| WOS记录号 | WOS:000678401900008
|
| 出版者 | |
| EI入藏号 | 20212210415856
|
| EI主题词 | Catalysis
; Catalysts
; Chlorine compounds
; Ligands
|
| EI分类号 | Nonferrous Metals and Alloys excluding Alkali and Alkaline Earth Metals:549.3
; Physical Chemistry:801.4
; Chemical Reactions:802.2
; Chemical Agents and Basic Industrial Chemicals:803
; Chemical Products Generally:804
|
| ESI学科分类 | CHEMISTRY
|
| Scopus记录号 | 2-s2.0-85106511948
|
| 来源库 | Scopus
|
| 引用统计 |
被引频次[WOS]：11
|
| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/229628 |
| 专题 | 理学院_化学系 前沿与交叉科学研究院 深圳格拉布斯研究院 |
| 作者单位 | 1.Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis,Southern University of Science and Technology,Shenzhen,518055,China 2.Shenzhen Grubbs Institute,Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen,518055,China 3.Academy for Advanced Interdisciplinary Studies,Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China |
| 第一作者单位 | 南方科技大学; 化学系; 深圳格拉布斯研究院 |
| 通讯作者单位 | 南方科技大学; 化学系; 前沿与交叉科学研究院; 深圳格拉布斯研究院 |
| 第一作者的第一单位 | 南方科技大学 |
| 推荐引用方式 GB/T 7714 |
Li，Zhuang,Cheng，Xian Yan,Yang，Ning Yuan,et al. A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral Multidentate N, N, P-Ligand[J]. ORGANOMETALLICS,2021,40(14):2215–2219.
|
| APA |
Li，Zhuang.,Cheng，Xian Yan.,Yang，Ning Yuan.,Chen，Ji Jun.,Tang，Wen Yue.,...&Liu，Xin Yuan.(2021).A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral Multidentate N, N, P-Ligand.ORGANOMETALLICS,40(14),2215–2219.
|
| MLA |
Li，Zhuang,et al."A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral Multidentate N, N, P-Ligand".ORGANOMETALLICS 40.14(2021):2215–2219.
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| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | 操作 | |
| A-Cobalt-Catalyzed-E（1219KB） | -- | -- | 限制开放 | -- | ||
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