Hydrophobic Surface Coating Can Reduce Toxicity of Zinc Oxide Nanoparticles to the Marine Copepod Tigriopus japonicus

Lai，Racliffe Weng Seng1,2; Kang，Hye Min3; Zhou，Guang Jie1,2; Yung，Mana Man Na2; He，Yan Ling4,5; Ng，Alan Man Ching4; Li，Xiao Yan6; Djurišić，Aleksandra B.5; Lee，Jae Seong3; Leung，Kenneth Mei Yee1,2

2021

10.1021/acs.est.1c01300

ENVIRONMENTAL SCIENCE & TECHNOLOGY   影响因子和分区

0013-936X

1520-5851

Coated zinc oxide nanoparticles (ZnO-NPs) are more commonly applied in commercial products but current risk assessments mostly focus on bare ZnO-NPs. To investigate the impacts of surface coatings, this study examined acute and chronic toxicities of six chemicals, including bare ZnO-NPs, ZnO-NPs with three silane coatings of different hydrophobicity, zinc oxide bulk particles (ZnO-BKs), and zinc ions (Zn-IONs), toward a marine copepod, Tigriopus japonicus. In acute tests, bare ZnO-NPs and hydrophobic ZnO-NPs were less toxic than hydrophilic ZnO-NPs. Analyses of the copepod's antioxidant gene expression suggested that such differences were governed by hydrodynamic size and ion dissolution of the particles, which affected zinc bioaccumulation in copepods. Conversely, all test particles, except the least toxic hydrophobic ZnO-NPs, shared similar chronic toxicity as Zn-IONs because they mostly dissolved into zinc ions at low test concentrations. The metadata analysis, together with our test results, further suggested that the toxicity of coated metal-associated nanoparticles could be predicted by the hydrophobicity and density of their surface coatings. This study evidenced the influence of surface coatings on the physicochemical properties, toxicity, and toxic mechanisms of ZnO-NPs and provided insights into the toxicity prediction of coated nanoparticles from their coating properties to improve their future risk assessment and management.

aggregation functionalization intrinsic growth rate ion dissolution metadata analysis oxidative stress predictive model surface modification

SCI ; EI

英语

NI论文

其他

WOS:000654292200039

20212210415299

Biochemistry ; Gene expression ; Hydrophobicity ; II-VI semiconductors ; Ions ; Metal nanoparticles ; Oxide minerals ; Particle size analysis ; Physicochemical properties ; Risk assessment ; Surface chemistry ; Toxicity ; Zinc coatings ; ZnO nanoparticles

Health Care:461.7 ; Biology:461.9 ; Minerals:482.2 ; Nanotechnology:761 ; Biochemistry:801.2 ; Physical Chemistry:801.4 ; Inorganic Compounds:804.2 ; Coating Materials:813.2 ; Accidents and Accident Prevention:914.1 ; Physical Properties of Gases, Liquids and Solids:931.2 ; Materials Science:951

ENVIRONMENT/ECOLOGY

2-s2.0-85106503560

Scopus

1.State Key Laboratory of Marine Pollution,Department of Chemistry,City University of Hong Kong,Hong Kong,Hong Kong
2.The Swire Institute of Marine Science,School of Biological Sciences,The University of Hong Kong,Hong Kong,Hong Kong
3.Department of Biological Science,Sungkyunkwan University,Suwon,16419,South Korea
4.Department of Physics,The Southern University of Science and Technology,Shenzhen,518055,China
5.Department of Physics,The University of Hong Kong,Hong Kong,Hong Kong
6.Department of Civil Engineering,The University of Hong Kong,Hong Kong,Hong Kong

Lai，Racliffe Weng Seng,Kang，Hye Min,Zhou，Guang Jie,et al. Hydrophobic Surface Coating Can Reduce Toxicity of Zinc Oxide Nanoparticles to the Marine Copepod Tigriopus japonicus[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2021,55:6917-6925.

Lai，Racliffe Weng Seng.,Kang，Hye Min.,Zhou，Guang Jie.,Yung，Mana Man Na.,He，Yan Ling.,...&Leung，Kenneth Mei Yee.(2021).Hydrophobic Surface Coating Can Reduce Toxicity of Zinc Oxide Nanoparticles to the Marine Copepod Tigriopus japonicus.ENVIRONMENTAL SCIENCE & TECHNOLOGY,55,6917-6925.

Lai，Racliffe Weng Seng,et al."Hydrophobic Surface Coating Can Reduce Toxicity of Zinc Oxide Nanoparticles to the Marine Copepod Tigriopus japonicus".ENVIRONMENTAL SCIENCE & TECHNOLOGY 55(2021):6917-6925.