| 题名 | The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study |
| 作者 | |
| 通讯作者 | He, Yitao |
| 发表日期 | 2021-08-01
|
| DOI | |
| 发表期刊 | |
| ISSN | 1359-5237
|
| EISSN | 1473-5725
|
| 卷号 | 26期号:4 |
| 摘要 | Objective Our study aimed to evaluate the effect of fluoxetine on morning blood pressure surge (MBPS) in patients with ischemic stroke. Methods A total of 30 patients with acute ischemic stroke, 15 in the control group and 15 in the treatment group, were enrolled. Two patients in the control group and one in the treatment group were lost during follow-up. The patients in the treatment group were treated with fluoxetine (20 mg per day for 3 months) based on the treatments in the control group. Baseline characteristics, Patient Health Questionnaire 9 (PHQ-9) items scale score, mean blood pressure and MBPS were evaluated before and after treatment, and the correlation between the improvements of PHQ-9 scale score and MBPS was also analyzed. Results The mean SBP and the systolic and diastolic MBPS in the treatment group were significantly lower than that in the control group after 3 months of treatment (P = 0.024, P = 0.022, P = 0.001, respectively). Besides, the improvement of PHQ-9 scale score was significantly higher in the treatment group than in the control group (P = 0.049). There was no significant correlation between the improvement of systolic or diastolic MBPS and the improvement of PHQ-9 scale score in the treatment group (P = 0.289 and P = 0.206, respectively). Conclusion Fluoxetine might improve MBPS in patients with ischemic stroke. |
| 关键词 | |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 学校署名 | 第一
; 通讯
|
| 资助项目 | National Natural Science Foundation of China[82071463]
; Medical Science and Technology Foundation of Guangdong Province, China[A2019442]
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| WOS研究方向 | Cardiovascular System & Cardiology
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| WOS类目 | Peripheral Vascular Disease
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| WOS记录号 | WOS:000670036100008
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| 出版者 | |
| ESI学科分类 | CLINICAL MEDICINE
|
| 来源库 | Web of Science
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| 引用统计 |
被引频次[WOS]：3
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| 成果类型 | 期刊论文 |
| 条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/240175 |
| 专题 | 南方科技大学第一附属医院 |
| 作者单位 | Jinan Univ, Southern Univ Sci & Technol, Dept Neurol,Affiliated Hosp 1, Shenzhen Peoples Hosp,Clin Med Coll 2, Shenzhen, Guangdong, Peoples R China |
| 第一作者单位 | 南方科技大学第一附属医院 |
| 通讯作者单位 | 南方科技大学第一附属医院 |
| 第一作者的第一单位 | 南方科技大学第一附属医院 |
| 推荐引用方式 GB/T 7714 |
He, Yitao,Deng, Jian,Zhang, Yaqing,et al. The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study[J]. BLOOD PRESSURE MONITORING,2021,26(4).
|
| APA |
He, Yitao,Deng, Jian,Zhang, Yaqing,Cai, Zhili,Zhang, Hui,&Guo, Yi.(2021).The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study.BLOOD PRESSURE MONITORING,26(4).
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| MLA |
He, Yitao,et al."The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study".BLOOD PRESSURE MONITORING 26.4(2021).
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| 条目包含的文件 | 条目无相关文件。 | |||||
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