南方科技大学知识苑(SUSTech KC): Organocatalytic Enantioselective Construction of Acyclic N,N-Acetals via Aza-Addition of Arylamines to Ketimines

题名	Organocatalytic Enantioselective Construction of Acyclic N,N-Acetals via Aza-Addition of Arylamines to Ketimines
作者	Lin, Xiao 1; Ge, Keli 4; He, Ningning 4; Chen, Xuling2,3 ; Li, Pengfei2,3 ; Dong, Mingxin 1; Li, Wenjun 1
通讯作者	Li, Pengfei; Dong, Mingxin; Li, Wenjun
发表日期	2021-07-29
DOI	10.1002/adsc.202100600
发表期刊	ADVANCED SYNTHESIS & CATALYSIS 影响因子和分区
ISSN	1615-4150
EISSN	1615-4169
卷号	363页码:4332-4337
摘要	A chiral phosphoric acid catalyzed enantioselective aza-addition of arylamines to ketimines has been developed for the construction of chiral acyclic N,N-acetal motifs. Under the standard conditions, arylamines reacted smoothly with ketimines from isoquinoline-1,3-dione to afford a series of acyclic N,N-acetals in 82-99% yield with 80-96% ee.
关键词	n,N-acetal Arylamine Enantioselectivity Ketimine Organocatalysis
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	通讯
资助项目	Special Funds of the Taishan Scholar Program of Shandong Province[tsqn201812047] ; Natural Science Foundation of Shandong Province[ZR2017JL011] ; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
WOS研究方向	Chemistry
WOS类目	Chemistry, Applied ; Chemistry, Organic
WOS记录号	WOS:000678805200001
出版者	WILEY-V C H VERLAG GMBH
来源库	Web of Science
引用统计	被引频次[WOS]：5
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/242041
专题	深圳格拉布斯研究院理学院_化学系
作者单位	1.Qingdao Univ, Sch Pharm, Dept Med Chem, Qingdao 266021, Shandong, Peoples R China 2.Southern Univ Sci & Technol SUSTech, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China 3.Southern Univ Sci & Technol SUSTech, Dept Chem, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China 4.Qingdao Univ, Sch Basic Med, Qingdao 266021, Shandong, Peoples R China
通讯作者单位	深圳格拉布斯研究院; 化学系
推荐引用方式 GB/T 7714	Lin, Xiao,Ge, Keli,He, Ningning,et al. Organocatalytic Enantioselective Construction of Acyclic N,N-Acetals via Aza-Addition of Arylamines to Ketimines[J]. ADVANCED SYNTHESIS & CATALYSIS,2021,363:4332-4337.
APA	Lin, Xiao.,Ge, Keli.,He, Ningning.,Chen, Xuling.,Li, Pengfei.,...&Li, Wenjun.(2021).Organocatalytic Enantioselective Construction of Acyclic N,N-Acetals via Aza-Addition of Arylamines to Ketimines.ADVANCED SYNTHESIS & CATALYSIS,363,4332-4337.
MLA	Lin, Xiao,et al."Organocatalytic Enantioselective Construction of Acyclic N,N-Acetals via Aza-Addition of Arylamines to Ketimines".ADVANCED SYNTHESIS & CATALYSIS 363(2021):4332-4337.