南方科技大学知识苑(SUSTech KC): Impact of the Host-Microbiome on Osteomyelitis Pathogenesis

题名	Impact of the Host-Microbiome on Osteomyelitis Pathogenesis
作者	Chen, Jun1 ; Xiong, Ailin 2; Ma, Yuhao1 ; Qin, Chenghe 2; Ho, Chun Loong1
通讯作者	Ho, Chun Loong
发表日期	2021-08-09
DOI	10.3389/fmolb.2021.702484
发表期刊	FRONTIERS IN MOLECULAR BIOSCIENCES 影响因子和分区
EISSN	2296-889X
卷号	8
摘要	The microbiome is a collection of genomes from microbiota, including all microorganisms in a niche, through direct and indirect interactions with the host. Certain microorganisms can exist in areas conventionally considered to be sterile, such as the bone matrix. Osseous microbiota dysbiosis caused by host-microbiome perturbation or external infections may ultimately lead to osteomyelitis, a bone inflammatory disorder. Our review covers the current discoveries on the impact of host-microbiome on osteomyelitis and some common osseous diseases. Some studies suggest that the microbiotas from both osseous and non-osseous tissues (e.g., blood or gut) impact the pathogenicity of osteomyelitis and other osseous diseases (e.g., rheumatoid arthritis). We believe that this review will provide readers with a better understanding on the role of the microbiome to the host's bone health.
关键词	microbiome osteomyelitis direct interaction indirect interaction pathogenesis
相关链接	[来源记录]
收录类别	SCI
语种	英语
学校署名	第一 ; 通讯
资助项目	Shenzhen Institutes of Advanced Technology External Funds[DWKF20190001] ; National Natural Science Foundation of China[22050410270] ; Guangdong Innovative Projects for the Characteristics of General Colleges and Universities[2018KTSCX200] ; Guangdong Innovative and Entrepreneurial Research Team Program[2019ZT08Y191]
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:000685088400003
出版者	FRONTIERS MEDIA SA
来源库	Web of Science
引用统计	被引频次[WOS]：9
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/244937
专题	工学院_生物医学工程系
作者单位	1.Southern Univ Sci & Technol SUSTech, Dept Biomed Engn, Shenzhen, Peoples R China 2.Guangdong Second Prov Gen Hosp, Dept Orthopaed Trauma, Guangzhou, Peoples R China
第一作者单位	生物医学工程系
通讯作者单位	生物医学工程系
第一作者的第一单位	生物医学工程系
推荐引用方式 GB/T 7714	Chen, Jun,Xiong, Ailin,Ma, Yuhao,et al. Impact of the Host-Microbiome on Osteomyelitis Pathogenesis[J]. FRONTIERS IN MOLECULAR BIOSCIENCES,2021,8.
APA	Chen, Jun,Xiong, Ailin,Ma, Yuhao,Qin, Chenghe,&Ho, Chun Loong.(2021).Impact of the Host-Microbiome on Osteomyelitis Pathogenesis.FRONTIERS IN MOLECULAR BIOSCIENCES,8.
MLA	Chen, Jun,et al."Impact of the Host-Microbiome on Osteomyelitis Pathogenesis".FRONTIERS IN MOLECULAR BIOSCIENCES 8(2021).