Latticed Channel Model of Touchable Communication over Capillary Microcirculation Network

Zhou, Yu1,2; Chen, Yifan1,3; Murch, Ross2

10.1109/GLOCOM.2018.8647980

2018

2334-0983

978-1-5386-4728-8

2018 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM)

1-6

9-13 Dec. 2018

Abu Dhabi, United arab emirates

345 E 47TH ST, NEW YORK, NY 10017 USA

IEEE

Recent progress on bioresorbable and biocompatible miniature systems provides prospects for developing novel nanobots operating inside the human body. These nanoscale systems are expected to dissolve in vivo and cause no side effect after completing their tasks. Motivated by these advancements, we have developed the analytical framework of touchable communication (TouchCom) to describe the process of targeted drug delivery (TDD) using physically transient nanobots. Built upon our previous work, we develop a novel latticed channel model of TouchCom for an interconnected capillary network near a targeted tumor area. Specifically, we propose a two-dimensional grid to synthesize the microcirculation environment, which is used to describe the propagation process of nanobots. Based on this model, we consider the influence of blood pressure on the efficiency of TDD, and introduce a compensation strategy with the help of an external guiding field to mitigate the misalignment between the direction of blood pressure and the tumor location.

Touchable communication latticed microcirculation network targeted drug delivery molecular communication

第一 ; 通讯

英语

CPCI-S ; EI

Engineering ; Telecommunications

Engineering, Electrical & Electronic ; Telecommunications

WOS:000465774305036

20191306708691

Biocompatibility ; Blood pressure ; Blood vessels ; Controlled drug delivery ; Microcirculation ; Nanorobots ; Tumors

Bioengineering and Biology:461 ; Robotics:731.5

Web of Science

1.Southern Univ Sci & Technol, Dept Elect & Elect Engn, Shenzhen, Peoples R China
2.Hong Kong Univ Sci & Technol, Dept Elect & Comp Engn, Hong Kong, Peoples R China
3.Univ Waikato, Fac Sci & Engn, Hamilton, New Zealand

Zhou, Yu,Chen, Yifan,Murch, Ross. Latticed Channel Model of Touchable Communication over Capillary Microcirculation Network[C]. 345 E 47TH ST, NEW YORK, NY 10017 USA:IEEE,2018:1-6.