A Nano-Filter-Integrated CMOS Image Sensor for Fluorescent Biomedical Imaging

Jiang, Yu1,2; Yu, Hao3; Fu, Xiaojian4; Hettiarachchi, Chathuranga1; Xu, He4; Li, Ye4; Tien Hoa Nguyen1; Dong, Longtao3; Dang, Cuong1; Zhang, Qing1

10.1109/BIOCAS.2018.8584706

2018

2163-4025

978-1-5386-3604-6

2018 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS): ADVANCED SYSTEMS FOR ENHANCING HUMAN HEALTH

683-686

17-19 Oct. 2018

Cleveland, OH, United states

345 E 47TH ST, NEW YORK, NY 10017 USA

IEEE

This paper presents a fluorescent image sensor with the integrated plasmonic nano-filter using metal layers in CMOS. The readout circuit is fully integrated with a high-gain pixel-level capacitive trans-impedance amplifier (CTIA), column-level amplifier, and correlated double sampling (CDS). The nano-filter achieved 51-dB simulated rejection ratio for 467-nm excitation light and 820-nm emission light. Considering low photodiode quantum efficiency and interference, a 24.2-dB system rejection ratio was achieved in measurement. In addition, liquid samples with/without PbS quantum dots (QDs) can be identified with 22-dB transmittance difference.

Optical filters Fluorescence Metals Photodiodes Semiconductor device measurement Image sensors Wavelength measurement

其他

英语

CPCI-S ; EI

Computer Science ; Engineering

Computer Science, Information Systems ; Engineering, Biomedical ; Engineering, Electrical & Electronic

WOS:000458897900177

20190606461298

CMOS integrated circuits ; Fluorescence imaging ; Image sensors ; IV-VI semiconductors ; Lead compounds ; Medical imaging ; Pixels ; Plasmonics ; Semiconductor quantum dots

Semiconductor Devices and Integrated Circuits:714.2 ; Imaging Techniques:746 ; Nanotechnology:761 ; Solid State Physics:933

Web of Science

1.Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore, Singapore
2.CINTRA CNRS NTU THALES, UMI 3288, Res Techno Plaza,50 Nanyang Dr, Singapore, Singapore
3.Southern Univ Sci & Technol, Shenzhen, Peoples R China
4.Southeast Univ, Nanjing, Jiangsu, Peoples R China

Jiang, Yu,Yu, Hao,Fu, Xiaojian,et al. A Nano-Filter-Integrated CMOS Image Sensor for Fluorescent Biomedical Imaging[C]. 345 E 47TH ST, NEW YORK, NY 10017 USA:IEEE,2018:683-686.