Microfluidics for Biomedical Analysis

Yang, Yong1,2; Chen, Yong1; Tang, Hao1; Zong, Nan1; Jiang, Xingyu1,3,4,5

2019-09-10

10.1002/smtd.201900451

Small Methods   影响因子和分区

2366-9608

Many new techniques and materials have been applied to microfluidic systems in the past decade, and integrated microfluidic chips have become powerful platforms for realizing highly sensitive, high throughput, and low-cost analysis. This article reviews the latest advancements of microfluidic platforms for biological and biomedical analysis in the fields of fundamental biology research, clinical application, food safety, and environmental monitoring, with a focus on nucleic acid-based molecular diagnosis and protein-based immunodiagnosis. The combination of microfluidics with advanced techniques (e.g., nanotechnology, 3D printing, deep learning) would offer innovative new tools for bioanalyses. The current challenges and the future developments of microfluidic technologies for clinical applications are also discussed. It is anticipated that this review will be beneficial to promoting microfluidics toward a broad range of applications in the future.

biomarkers lab-on-a-chip microfluidics molecular diagnostics point-of-care testing

SCI ; EI

英语

第一 ; 通讯

Youth Innovation Promotion Association of the Chinese Academy of Sciences[2016323]

Chemistry ; Science & Technology - Other Topics ; Materials Science

Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary

WOS:000485913200001

WILEY-V C H VERLAG GMBH

20201808588232

Clinical research ; Nucleic acids ; Molecular biology ; 3D printers ; Lab-on-a-chip ; Diagnosis ; Deep learning ; Fluidic devices

Biological Materials and Tissue Engineering:461.2 ; Ergonomics and Human Factors Engineering:461.4 ; Medicine and Pharmacology:461.6 ; Biology:461.9 ; Hydraulic Equipment and Machinery:632.2 ; Microfluidics:632.5.1 ; Semiconductor Devices and Integrated Circuits:714.2 ; Control Equipment:732.1 ; Printing Equipment:745.1.1 ; Biochemistry:801.2 ; Organic Compounds:804.1

Web of Science

1.Southern Univ Sci & Technol SUSTech, Dept Biomed Engn, Shenzhen 518055, Peoples R China
2.Southern Univ Sci & Technol SUSTech, SUSTech Acad Adv Interdisciplinary Studies, Shenzhen 518055, Peoples R China
3.Natl Ctr NanoSci & Technol, Beijing Engn Res Ctr BioNanotechnol, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China
4.Natl Ctr NanoSci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China
5.Univ Chinese Acad Sci, Sch Nanosci & Technol, Beijing 100049, Peoples R China

Yang, Yong,Chen, Yong,Tang, Hao,et al. Microfluidics for Biomedical Analysis[J]. Small Methods,2019,4.

Yang, Yong,Chen, Yong,Tang, Hao,Zong, Nan,&Jiang, Xingyu.(2019).Microfluidics for Biomedical Analysis.Small Methods,4.

Yang, Yong,et al."Microfluidics for Biomedical Analysis".Small Methods 4(2019).