Does objectively measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis

Qiu, Shanhu1; Cai, Xue2; Jia, Lijing1; Sun, Zilin3; Wu, Tongzhi3,4,5; Wendt, Janine6; Steinacker, Jurgen Michael6; Schumann, Uwe6

2021-11-01

10.1093/ehjqcco/qcaa051

European Heart Journal-Quality of Care and Clinical Outcomes   影响因子和分区

2058-5225

2058-1742

["Aims Current physical activity guidelines emphasize little on light-intensity physical activity (LPA) in terms of reducing the risk of cardiovascular mortality. This meta-analysis aimed to bridge this gap by assessing their association using objectively measured LPA data.","Methods and results Databases of PubMed and Scopus were searched to April 2020 for prospective cohort studies that reported the association of LPA assessed by activity monitors with the risk of cardiovascular mortality in the general population. Multivariable-adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Dose-response and subgroup analyses were also performed. Six cohort studies with seven datasets enrolling 13 960 participants were included. LPA was all measured by accelerometers. The HR of LPA per 30min/day for cardiovascular mortality was pooled to be 0.80 (95% CI 0.67-0.96). This association was non-linearly shaped (P-nonlinearity < 0.01) and unaffected by sex difference. Moreover, substituting LPA for sedentary time of 30min/day lowered the risk of cardiovascular mortality by 16% (95% CI 0.73-0.96). Results showed further that LPA was inferior to moderate-to-vigorous physical activity in reducing the risk of cardiovascular mortality when performed with an equal time-length set at 30min/day (HR 0.83 vs. 0.54, P-comparison = 0.046), but became comparable if at an equal activity-amount set at 150 metabolic equivalents-min/day (HR 0.67 vs. 0.54, P-comparison = 0.41).","Conclusion LPA shows potential in reducing the risk of cardiovascular mortality, and interventions targeting at LPA improvement are worth being encouraged."]

Light-intensity physical activity Cardiovascular mortality Meta-analysis

SCI

英语

第一 ; 通讯

Cardiovascular System & Cardiology

Cardiac & Cardiovascular Systems

WOS:000701460000010

OXFORD UNIV PRESS

Web of Science

1.Southern Univ Sci & Technol, Clin Med Coll 2, Shenzhen Peoples Hosp, Dept Endocrinol,Jinan Univ,Affiliated Hosp 1, Dongmen North Rd 1017, Shenzhen 518020, Peoples R China
2.Peking Univ, Sch Nursing, Xueyuan Rd 38, Beijing 100191, Peoples R China
3.Southeast Univ, Zhongda Hosp, Sch Med, Dept Endocrinol,Inst Diabet, Dingjiaqiao 87, Nanjing 210009, Peoples R China
4.Univ Adelaide, Adelaide Med Sch, Level 5 Adelaide Hlth & Med Sci Bldg, Adelaide, SA 5005, Australia
5.Univ Adelaide, Ctr Res Excellence Translating Nutr Sci Good Hlth, Level 5 Adelaide Hlth & Med Sci Bldg, Adelaide, SA 5005, Australia
6.Ulm Univ, Div Sports & Rehabil Med, Med Ctr, Leimgrubenweg 14, D-89075 Ulm, Germany

Qiu, Shanhu,Cai, Xue,Jia, Lijing,et al. Does objectively measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis[J]. European Heart Journal-Quality of Care and Clinical Outcomes,2021,7(5).

Qiu, Shanhu.,Cai, Xue.,Jia, Lijing.,Sun, Zilin.,Wu, Tongzhi.,...&Schumann, Uwe.(2021).Does objectively measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis.European Heart Journal-Quality of Care and Clinical Outcomes,7(5).

Qiu, Shanhu,et al."Does objectively measured light-intensity physical activity reduce the risk of cardiovascular mortality? A meta-analysis".European Heart Journal-Quality of Care and Clinical Outcomes 7.5(2021).