Transition metal-catalyzed conversion of aldehydes to ketones

Yan，Zijuan1; Shao，Pan Lin2; Qiang，Qing1; Liu，Feipeng1; Wang，Xuchao1; Li，Yongjie1; Rong，Zi Qiang1

2021

10.1016/j.cclet.2021.08.112

CHINESE CHEMICAL LETTERS   影响因子和分区

1001-8417

1878-5964

Ketones are one of the most important classes of organic compounds, and widely present in various pharmacological compounds, biologically active molecules and functional materials. Over the past few decades, transition metal-catalyzed conversion of aldehydes has been found to be a powerful method. With the continuous development in recent years, it has become an efficient and uncomplicated strategy for constructing ketones. There are four major mechanisms for transition metal-catalyzed ketone synthesis from aldehyde: (1) carbonyl-Heck reaction, that is 1,2-insertion of organometal species to aldehydic C=O double bond, (2) direct insertion of transition metal catalysts to aldehydic C-H bond, (3) aldehyde as acyl radical, (4) aldehyde as carbon radical acceptor. This article summarizes related reports on the transformations of aldehydes to generate corresponding ketones under different reaction conditions.

C-H bond functionalization Direct conversion Homogeneous catalysis Ketone synthesis Transition metal catalysis

SCI

英语

其他

National Natural Science Foundation of China[21801206] ; Chunhui Program of Ministry of Education of China[5180210003] ; Program for Young Talents of Shaanxi Province[5113190023] ; Department of Science & Technology of Shannxi Province[2020GXLH-Z-015] ; Northwestern Polytechnical University[2020GXLH-Z-015] ; Science, Technology and Innovation Commission of Shenzhen[JCYJ20190809160211372]

Chemistry

Chemistry, Multidisciplinary

WOS:000772416400009

ELSEVIER SCIENCE INC

CHEMISTRY

2-s2.0-85115151607

Scopus

1.Frontiers Science Center for Flexible Electronics (FSCFE),Shaanxi Institute of Flexible Electronics (SIFE) & Shaanxi Institute of Biomedical Materials and Engineering (SIBME),Northwestern Polytechnical University (NPU),Xi'an,710072,China
2.College of Innovation and Entrepreneurship,Southern University of Science and Technology,Shenzhen,518055,China

Yan，Zijuan,Shao，Pan Lin,Qiang，Qing,et al. Transition metal-catalyzed conversion of aldehydes to ketones[J]. CHINESE CHEMICAL LETTERS,2021,33(3).

Yan，Zijuan.,Shao，Pan Lin.,Qiang，Qing.,Liu，Feipeng.,Wang，Xuchao.,...&Rong，Zi Qiang.(2021).Transition metal-catalyzed conversion of aldehydes to ketones.CHINESE CHEMICAL LETTERS,33(3).

Yan，Zijuan,et al."Transition metal-catalyzed conversion of aldehydes to ketones".CHINESE CHEMICAL LETTERS 33.3(2021).