The association between long-term exposure to ambient fine particulate matter and glaucoma: A nation-wide epidemiological study among Chinese adults

Yang，Xueli1,2; Yang，Ze1,2; Liu，Yuanyuan3,4; Chen，Xi1,2; Yao，Baoqun3,4; Liang，Fengchao5; Shan，Anqi1,2; Liu，Fangchao6,7; Chen，Song3; Yan，Xiaochang8; Huang，Jianfeng6,7; Bo，Shaoye9; Liu，Yang10; Tang，Naijun1,2; Gu，Dongfeng5,6,7; Yan，Hua3,4

2021-09-01

10.1016/j.ijheh.2021.113858

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH   影响因子和分区

1438-4639

1618-131X

Background: A growing body of evidence has confirmed the association between fine particulate matter (PM) and ocular diseases, but little is known on the effect of long-term PM exposure on glaucoma. Methods: A national cross-sectional study of the Rural Epidemiology for Glaucoma was conducted in 10 provinces of China, and 33,701 adults aged 40 years or more were included. A satellite-based model at 1-km resolution level was used to estimate PM concentrations which were assigned to each participant according to geocoded home addresses. Logistic regression model was performed to investigate associations of long-term PM exposure with glaucoma and its subtypes. Results: Estimated PM concentrations ranged from 28.0 to 96.4 μg/m. For each 10 μg/m increment in PM, the adjusted odds ratios (ORs) were 1.07 (95% CI: 1.00–1.15) and 1.14 (95% CI: 1.02–1.26) for glaucoma and primary angle-closure glaucoma (PACG), respectively. A positive but non-significant association (OR = 1.05, 95% CI: 0.92–1.18) was detected between long-term exposure to PM and odds of primary open-angle glaucoma. The middle aged residents and non-smokers were more sensitive to the adverse effects of PM. Conclusions: Long-term PM exposure was associated with glaucoma and PACG in Chinese adults, which provided new insights on adverse ophthalmic effect of PM.

Eye PM2.5 Satellite-based model

SCI

英语

其他

National Natural Science Foundation of China[82020108007,81830026] ; Beijing-Tianjin Hebei Special Project[19JCZDJC64300(Z)] ; National Key Research and Development Program of China["2016YFC0206503","2017YFC0211605"] ; National Institute of Environmental Health Sciences of the National Institutes of Health[1R01ES032140]

Public, Environmental & Occupational Health ; Infectious Diseases

Public, Environmental & Occupational Health ; Infectious Diseases

WOS:000710922400004

ELSEVIER GMBH

SOCIAL SCIENCES, GENERAL

2-s2.0-85116560460

Scopus

1.Department of Occupational and Environmental Health,School of Public Health,Tianjin Medical University,Tianjin,300070,China
2.Tianjin Key Laboratory of Environment,Nutrition,and Public Health,Tianjin Medical University,Tianjin,300070,China
3.Department of Ophthalmology,Tianjin Medical University General Hospital,Tianjin,300052,China
4.Tianjin Medical University,Tianjin,300070,China
5.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,518055,China
6.Key Laboratory of Cardiovascular Epidemiology,Chinese Academy of Medical Sciences,Beijing,100037,China
7.Department of Epidemiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100037,China
8.National School of Development,Peking University,Beijing,100871,China
9.China Foundation for Disabled Persons,Beijing,Dongcheng District,100006,China
10.Gangarosa Department of Environmental Health,Rollins School of Public Health,Emory University,Atlanta,30322,United States

Yang，Xueli,Yang，Ze,Liu，Yuanyuan,et al. The association between long-term exposure to ambient fine particulate matter and glaucoma: A nation-wide epidemiological study among Chinese adults[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,2021,238.

Yang，Xueli.,Yang，Ze.,Liu，Yuanyuan.,Chen，Xi.,Yao，Baoqun.,...&Yan，Hua.(2021).The association between long-term exposure to ambient fine particulate matter and glaucoma: A nation-wide epidemiological study among Chinese adults.INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,238.

Yang，Xueli,et al."The association between long-term exposure to ambient fine particulate matter and glaucoma: A nation-wide epidemiological study among Chinese adults".INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 238(2021).