Highly chemoselective hydrogenation of cyclic imides to omega-hydroxylactams or omega-hydroxyamides catalyzed by iridium catalysts

Wu, Chao1,2; Wang, Jiang2; Zhang, Xumu2; Zhang, Runtong2; Ma, Baode2

2021-09-01

10.1039/d1qo01100f

Organic Chemistry Frontiers   影响因子和分区

2052-4129

Several novel ferrocene-based PNN ligands were prepared, which were found to be highly effective catalysts (TON up to 50 000) for the homogeneous hydrogenation of cyclic imides with iridium. The hydrogenation mode (type I: ring opening/type II: non-ring opening) could be finely tuned by tiny changes in the ligands. Using this straightforward strategy, a plethora of omega-hydroxylactams and omega-hydroxyamides with different functional groups were obtained in high yield.

SCI ; EI

英语

通讯

Free Exploration Fund from the Science and Technology Innovation Committee of Shenzhen[JCYJ20170817104824122] ; National Natural Science Foundation of China[22001113]

Chemistry

Chemistry, Organic

WOS:000705668000001

ROYAL SOC CHEMISTRY

20214911272691

Amines ; Catalysts ; Hydrogenation ; Iridium ; Iron compounds ; Organometallics

Precious Metals:547.1 ; Physical Chemistry:801.4 ; Chemical Reactions:802.2 ; Chemical Agents and Basic Industrial Chemicals:803 ; Chemical Products Generally:804 ; Organic Compounds:804.1

Web of Science

1.Harbin Inst Technol, Sch Chem & Chem Engn, Harbin 150001, Peoples R China
2.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518000, Peoples R China

Wu, Chao,Wang, Jiang,Zhang, Xumu,et al. Highly chemoselective hydrogenation of cyclic imides to omega-hydroxylactams or omega-hydroxyamides catalyzed by iridium catalysts[J]. Organic Chemistry Frontiers,2021,8:6530-6534.

Wu, Chao,Wang, Jiang,Zhang, Xumu,Zhang, Runtong,&Ma, Baode.(2021).Highly chemoselective hydrogenation of cyclic imides to omega-hydroxylactams or omega-hydroxyamides catalyzed by iridium catalysts.Organic Chemistry Frontiers,8,6530-6534.

Wu, Chao,et al."Highly chemoselective hydrogenation of cyclic imides to omega-hydroxylactams or omega-hydroxyamides catalyzed by iridium catalysts".Organic Chemistry Frontiers 8(2021):6530-6534.