Validity of SOFA score as a prognostic tool for critically ill elderly patients with acute infective endocarditis

Lin，Yaowang1; Liu，Feng1; Gong，Shuying1; Liao，Bihong1; Liu，Huadong1; Yuan，Jie1; Yu，Danqing2; Qin，Haiyan3; Wu，Meishan1; Dong，Shaohong1

2021-09-24

10.31083/J.RCM2203105

Reviews in Cardiovascular Medicine   影响因子和分区

1530-6550

2153-8174

The prognostic value of the sequential organ failure assessment (SOFA) score for critically ill elderly patients with acute infective endocarditis (IE) remains unknown. From January 2015 to December 2019, 111 elderly (≥65 years) patients with acute IE were consecutively included and divided into a low SOFA (<6) group (n = 71) and a high SOFA (≥6) group (n = 40). Endpoints included in-hospital and long-term (12-36 month) mortality. A high SOFA score was related to higher incidence of in-hospital mortality (30.0%) with an area under the curve (AUC) of 0.796. In multivariate analysis, age [odds ratio (OR) = 2.21, 95% confidence intervals (CI), 1.16-6.79, p = 0.040], SOFA ≥6 (OR = 6.38, 95% CI, 1.80-16.89, p = 0.004) and surgical treatment (OR = 0.21, 95% CI, 0.05-0.80, p = 0.021) were predictive of in-hospital mortality. A Cox proportional-hazards model identified age [Hazard ratios (HR)= 2.85, 95% CI, 1.11-7.37, p = 0.031], diabetes mellitus (HR = 3.99, 95% CI, 1.35-11.80, p = 0.013), SOFA ≥6 (OR = 3.38, 95% CI, 1.26-9.08, p = 0.001) and surgical treatment (HR = 0.24, 95% CI, 0.08-0.68, p = 0.021) as predictors of long-term mortality. A high SOFA score predicts a poor outcome including in-hospital and long-term mortality in critically ill elderly patients with acute IE.

Acute infective endocarditis Elderly patients In-hospital mortality Long-term mortality SOFA

SCI

英语

第一 ; 通讯

WOS:000702099800043

2-s2.0-85116760033

Scopus

1.Department of Cardiology,Shenzhen Cardiovascular Minimally Invasive Medical Engineering,Technology Research and Development Center,Shenzhen People's Hospital,The Second Clinical Medical College,Jinan University,The First Affiliated Hospital,Southern University of Science and Technology,Shenzhen,Guangdong,518020,China
2.Department of Cardiology,Guangdong General Hospital,Guangdong Academy of Sciences,Guangzhou,Guangdong,510650,China
3.Department of Health Management,Shenzhen People's Hospital,Shenzhen,Guangdong,518020,China

Lin，Yaowang,Liu，Feng,Gong，Shuying,et al. Validity of SOFA score as a prognostic tool for critically ill elderly patients with acute infective endocarditis[J]. Reviews in Cardiovascular Medicine,2021,22(3):967-973.

Lin，Yaowang.,Liu，Feng.,Gong，Shuying.,Liao，Bihong.,Liu，Huadong.,...&Dong，Shaohong.(2021).Validity of SOFA score as a prognostic tool for critically ill elderly patients with acute infective endocarditis.Reviews in Cardiovascular Medicine,22(3),967-973.

Lin，Yaowang,et al."Validity of SOFA score as a prognostic tool for critically ill elderly patients with acute infective endocarditis".Reviews in Cardiovascular Medicine 22.3(2021):967-973.