Clinical Value of the Elastographic Q-Analysis Score in Assisting Real-Time Elastography-Guided Prostate Biopsy: A Retrospective Study of 125 Patients

Ding, Zhimin1,2; Jiao, Yang1,2; Wu, Huaiyu1,2; Zhang, Lei1,2; Song, Hong1,2; Ni, Zhipeng1,2; Ye, Xiuqin1,2; Xu, Jinfeng1,2; Dong, Fajin1,2

2019-07

10.1002/jum.15075

JOURNAL OF ULTRASOUND IN MEDICINE   影响因子和分区

0278-4297

1550-9613

Objectives This study aimed to evaluate the clinical value of the elastographic Q-analysis score (EQS) in assisting real-time elastography- and transrectal US-guided prostate biopsy. Methods A total of 125 patients with 301 lesions were enrolled in this study; all were confirmed by pathologic results. The patients underwent transrectal US and elastographic examinations before biopsy. Elastographic Q-analysis score analysis software was used for measuring the mean EQS of the elastic images. First, the suspicious regions on elastography underwent biopsy. Then 12-core systematic prostate biopsy was performed. An EQS curve was used to calculate the mean EQS, and a receiver operating characteristic curve was drawn to find the cutoff point for the EQS to predict prostate cancer. Results Of the 301 lesions in this study, 125 were malignant, and 176 were benign. The mean EQS values of benign and malignant lesions +/- SD were 1.47 +/- 0.75 and 2.98 +/- 1.06, respectively. The difference was statistically significant (P < .05). The area under the receiver operating characteristic curve was 0.87. When the cutoff point was 1.95 for diagnosing malignant and benign lesions, the sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, and negative likelihood ratio were 83.5%, 84.4%, 76.8%, 89.2%, 5.35, and 0.20. Conclusions The EQS could be used as a way to predict benign and malignant lesions and thus could serve as guidance for adding targeted biopsy.

elastographic Q-analysis score elastography elastography-guided prostate biopsy prostate cancer transrectal ultrasound

SCI ; EI

英语

第一 ; 通讯

Guangdong Medical Research Fund[B2019112]

Acoustics ; Radiology, Nuclear Medicine & Medical Imaging

Acoustics ; Radiology, Nuclear Medicine & Medical Imaging

WOS:000474172800001

WILEY

20200908242276

Diseases ; Medical imaging ; Urology

Medicine and Pharmacology:461.6 ; Imaging Techniques:746

CLINICAL MEDICINE

Web of Science

1.Southern Univ Sci & Technol, Dept Ultrasound, Affiliated Hosp 1, 1017 Dongmen North Rd, Shenzhen 518020, Peoples R China
2.Jinan Univ, Clin Coll 2, Shenzhen Med Ultrasound Engn Ctr, Shenzhen Peoples Hosp, 1017 Dongmen North Rd, Shenzhen 518020, Peoples R China

Ding, Zhimin,Jiao, Yang,Wu, Huaiyu,et al. Clinical Value of the Elastographic Q-Analysis Score in Assisting Real-Time Elastography-Guided Prostate Biopsy: A Retrospective Study of 125 Patients[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2019,39(1):83-87.

Ding, Zhimin.,Jiao, Yang.,Wu, Huaiyu.,Zhang, Lei.,Song, Hong.,...&Dong, Fajin.(2019).Clinical Value of the Elastographic Q-Analysis Score in Assisting Real-Time Elastography-Guided Prostate Biopsy: A Retrospective Study of 125 Patients.JOURNAL OF ULTRASOUND IN MEDICINE,39(1),83-87.

Ding, Zhimin,et al."Clinical Value of the Elastographic Q-Analysis Score in Assisting Real-Time Elastography-Guided Prostate Biopsy: A Retrospective Study of 125 Patients".JOURNAL OF ULTRASOUND IN MEDICINE 39.1(2019):83-87.