NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging

Liao，Jiayan2; Yang，Liu1; Wu，Sitong1; Yang，Zhichao1; Zhou，Jiajia2; Jin，Dayong1,2; Guan，Ming1

2022-02-01

10.1016/j.jlumin.2021.118597

JOURNAL OF LUMINESCENCE   影响因子和分区

0022-2313

1872-7883

The second near-infrared window (1000–1700 nm, NIR-II) emissive lanthanide-doped nanoparticles excited by 808 nm laser are ideal for in vivo bioimaging due to their non-heating excitation. The study of 808 nm excited lanthanide-doped nanoparticles not only provides high-quality NIR-II imaging but also can promote in vivo multiplexed bioimaging under single excitation. Herein, we prepared three sets of typical 808 nm excited lanthanide-doped nanoparticles (NaYF: Nd@NaYF, NaErF@NaYF, and NaYbF: Er/Ce@NaYbF@NaYF: Yb/Nd) and then systematically compared their optical properties in the NIR-II window. Furthermore, we prepared water-soluble and biocompatible nanoprobes and achieved multiplexed NIR-II in vivo imaging in mice under single 808 nm excitation. These results highlight the potential of 808 nm excited lanthanide probes for physiological studies and biomedical applications.

808 nm excitation Lanthanide nanoparticles Near-infrared II

SCI ; EI

英语

通讯

National Natural Science Foundation of China (NSFC)[61729501] ; Major International (Regional) JointResearch Project of NSFC[51720105015] ; Science and Technology Innovation Commission of Shenzhen[KQTD20170810110913065] ; Australia China Science and Research Fund Joint Research Centre for Point-of-Care Testing["ACSRF658277","2017YFE0132300"]

Optics

Optics

WOS:000730170000003

ELSEVIER

20214711189004

Biocompatibility ; Laser excitation ; Mammals ; Medical applications ; Nanoparticles ; Optical properties ; Rare earth elements

Immunology:461.9.1 ; Rare Earth Metals:547.2 ; Light/Optics:741.1 ; Laser Applications:744.9 ; Nanotechnology:761 ; Physical Chemistry:801.4 ; Solid State Physics:933

PHYSICS

2-s2.0-85119202555

Scopus

1.UTS-SUStech Joint Research Centre for Biomedical Materials and Devices,Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen,518055,China
2.Institute for Biomedical Materials and Devices (IBMD),Faculty of Science,University of Technology Sydney,2007,Australia

Liao，Jiayan,Yang，Liu,Wu，Sitong,et al. NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging[J]. JOURNAL OF LUMINESCENCE,2022,242.

Liao，Jiayan.,Yang，Liu.,Wu，Sitong.,Yang，Zhichao.,Zhou，Jiajia.,...&Guan，Ming.(2022).NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging.JOURNAL OF LUMINESCENCE,242.

Liao，Jiayan,et al."NIR-II emissive properties of 808 nm-excited lanthanide-doped nanoparticles for multiplexed in vivo imaging".JOURNAL OF LUMINESCENCE 242(2022).