General One-Pot Method for Preparing Highly Water-Soluble and Biocompatible Photoinitiators for Digital Light Processing-Based 3D Printing of Hydrogels

Wang，Hui1; Zhang，Biao1; Zhang，Jianhong1; He，Xiangnan2; Liu，Fukang1; Cui，Jingjing1; Lu，Zhe1; Hu，Guang3; Yang，Jun1; Zhou，Zhe1; Wang，Runze1; Hou，Xingyu1; Ma，Luankexin1; Ren，Panyu1; Ge，Qi2; Li，Peng1; Huang，Wei1

2021

10.1021/acsami.1c15636

ACS Applied Materials & Interfaces   影响因子和分区

1944-8244

1944-8252

We report a facile but general method to prepare highly water-soluble and biocompatible photoinitiators for digital light processing (DLP)-based 3D printing of high-resolution hydrogel structures. Through a simple and straightforward one-pot procedure, we can synthesize a metal-phenyl(2,4,6-trimethylbenzoyl)phosphinates (M-TMPP)-based photoinitiator with excellent water solubility (up to ∼50 g/L), which is much higher than that of previously reported water-soluble photoinitiators. The M-TMPP aqueous solutions show excellent biocompatibility, which meets the prerequisite for biomedical applications. Moreover, we used M-TMPP to prepare visible light (405 nm)-curable hydrogel precursor solutions for 3D printing hydrogel structures with a high water content (80 wt %), high resolution (∼7 μm), high deformability (more than 80% compression), and complex geometry. The printed hydrogel structures demonstrate great potential in flexible electronic sensors due to the fast mechanical response and high stability under cyclic loadings.

3D printing biocompatible digital light processing hydrogel photoinitiator

SCI ; EI

英语

通讯

National Natural Science Foundation of China[21875189,51903210] ; Natural Science Basic Research Program of Shanxi[2020JQ-174] ; Key-Area Research and Development Program of Guangdong Province[2020B090923003] ; Open Project Foundation of National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization[SF202010] ; Innovation Foundation for Master Dissertation of Northwestern Polytechnical University[CX2020282] ; Innovation and Entrepreneurship Training Program for College Students of Northwestern Polytechnical University[S202010699534]

Science & Technology - Other Topics ; Materials Science

Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary

WOS:000751884800087

AMER CHEMICAL SOC

20214711204400

3D printers ; Hydrogels ; Light ; Medical applications

Immunology:461.9.1 ; Light/Optics:741.1 ; Printing Equipment:745.1.1 ; Colloid Chemistry:801.3 ; Chemical Products Generally:804

2-s2.0-85119424907

Scopus

1.Frontiers Science Center for Flexible Electronics (FSCFE),Xi'An Institute of Flexible Electronics (IFE),Xi'An Institute of Biomedical Materials and Engineering (IBME),Northwestern Polytechnical University,Xi'an,127 West Youyi Road,710072,China
2.Department of Mechanical and Energy Engineering,Southern University of Science and Technology,Shenzhen,518055,China
3.National and Local Joint Engineering Research Center for Mineral Salt Deep Utilization,Faculty of Chemical Engineering,Huaiyin Institute of Technology,Huaian,223003,China

Wang，Hui,Zhang，Biao,Zhang，Jianhong,et al. General One-Pot Method for Preparing Highly Water-Soluble and Biocompatible Photoinitiators for Digital Light Processing-Based 3D Printing of Hydrogels[J]. ACS Applied Materials & Interfaces,2021,13(46):55507-55516.

Wang，Hui.,Zhang，Biao.,Zhang，Jianhong.,He，Xiangnan.,Liu，Fukang.,...&Huang，Wei.(2021).General One-Pot Method for Preparing Highly Water-Soluble and Biocompatible Photoinitiators for Digital Light Processing-Based 3D Printing of Hydrogels.ACS Applied Materials & Interfaces,13(46),55507-55516.

Wang，Hui,et al."General One-Pot Method for Preparing Highly Water-Soluble and Biocompatible Photoinitiators for Digital Light Processing-Based 3D Printing of Hydrogels".ACS Applied Materials & Interfaces 13.46(2021):55507-55516.