Anti-pathogen stainless steel combating COVID-19

Liu，L. T.1,2; Chin，A. W.H.3,4; Yu，P.2; Poon，L. L.M.3,4,5; Huang，M. X.1

2021

10.1016/j.cej.2021.133783

CHEMICAL ENGINEERING JOURNAL   影响因子和分区

1385-8947

1873-3212

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits strong stability on conventional stainless steel (SS) surface, with infectious virus detected even after two days, posing a high risk of virus transmission via surface touching in public areas. In order to mitigate the surface toughing transmission, the present study develops the first SS with excellent anti-pathogen properties against SARS-COV-2. The stabilities of SARS-CoV-2, H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli) on the surfaces of Cu-contained SS, pure Cu, Ag-contained SS, and pure Ag were investigated. It is discovered that pure Ag and Ag-contained SS surfaces do not display apparent inhibitory effects on SARS-CoV-2 and H1N1. In comparison, both pure Cu and Cu-contained SS with a high Cu content exhibit significant antiviral properties. Significantly, the developed anti-pathogen SS with 20 wt% Cu can distinctly reduce 99.75% and 99.99% of viable SARS-CoV-2 on its surface within 3 and 6 h, respectively. In addition, the present anti-pathogen SS also exhibits an excellent inactivation ability for H1N1 influenza A virus (H1N1), and Escherichia coli (E.coli). Interestingly, the Cu ion concentration released from the anti-pathogen SS with 10 wt% and 20 wt% Cu was notably higher than the Ag ion concentration released from Ag and the Ag-contained SS. Lift buttons made of the present anti-pathogen SS are produced using mature powder metallurgy technique, demonstrating its potential applications in public areas and fighting the transmission of SARS-CoV-2 and other pathogens via surface touching.

Anti-pathogen COVID-19 H1N1 SARS-CoV-2 Stainless steel

SCI ; EI

英语

其他

Health and Medical Research Fund[COVID190116] ; National Institute of Allergy and Infectious Diseases[HHSN272201400006C] ; Shenzhen Science and Technology Innovation Committee[KQJSCX20180322152424539]

Engineering

Engineering, Environmental ; Engineering, Chemical

WOS:000795941600003

ELSEVIER SCIENCE SA

20214911283549

Escherichia coli ; Pathogens ; Powder metallurgy ; Silver ; Stainless steel ; Transmissions ; Viruses

Biology:461.9 ; Copper:544.1 ; Steel:545.3 ; Precious Metals:547.1 ; Mechanical Transmissions:602.2

ENGINEERING

2-s2.0-85120465177

Scopus

1.Department of Mechanical Engineering,The University of Hong Kong,Hong Kong,Pokfulam Road,Hong Kong
2.Department of Materials Science and Engineering,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Avenue,518000,China
3.School of Public Health,LKS Faculty of Medicine,The University of Hong Kong,Hong Kong,21 Sassoon Road,Hong Kong
4.Centre for Immunity and Infection,Hong Kong,Hong Kong Science Park,Hong Kong
5.HKU-Pasteur Research Pole,LKS Faculty of Medicine,The University of Hong Kong,Hong Kong,Hong Kong

Liu，L. T.,Chin，A. W.H.,Yu，P.,et al. Anti-pathogen stainless steel combating COVID-19[J]. CHEMICAL ENGINEERING JOURNAL,2021,433.

Liu，L. T.,Chin，A. W.H.,Yu，P.,Poon，L. L.M.,&Huang，M. X..(2021).Anti-pathogen stainless steel combating COVID-19.CHEMICAL ENGINEERING JOURNAL,433.

Liu，L. T.,et al."Anti-pathogen stainless steel combating COVID-19".CHEMICAL ENGINEERING JOURNAL 433(2021).