Highly selective and sensitive detection of mercury (II) and dopamine based on the efficient electrochemiluminescence of Ru(bpy)32+ with acridine orange as a coreactant

Saqib，Muhammad1,2; Bashir，Shahida3; Ali，Sajjad4; Hao，Rui1

2021

10.1016/j.jelechem.2021.115896

JOURNAL OF ELECTROANALYTICAL CHEMISTRY   影响因子和分区

1572-6657

1873-2569

Developing highly specific, rapid, and cost-effective electrochemiluminescence (ECL) methods capable of detecting multiple analytes remains a compelling research goal but it is still a substantial challenge due to narrow choice of ECL systems. In this study, efficient ECL detections were achieved by using anodic Ru(bpy)-acridine orange (AO) ECL system. In present system, dimethylamino substituent on acridine ring acts as active sites for strong ECL generation, while heterocyclic nitrogen atom (–N–) contributes to specific complex formation with metal ion. Accordingly, this anodic ECL method was exploited for highly sensitive detection of both mercury (II) (Hg) and dopamine (DA), with detection limits as low as 0.36 nM (linear range 0.01–50 μM) and 1.0 nM (linear range 0.01–10 μM), respectively. The mechanism of Hg detection was supported by density functional theory (DFT) calculations. Notably, the ECL method exhibit superior selectivity over numerous competing interfering agents. Moreover, the method achieved the detection of both targets in practical media with excellent recoveries (96.0–103.8%). Importantly, the method demonstrates potential advantages in terms of selectivity, sensitivity, rapidity, simplicity, and low cost. This work realizes a successful attempt to further expand the analytical applications of ECL systems and may initiate new thoughts in utilizing acridines in diverse ECL-based sensing and imaging applications.

Acridine orange Dopamine mercury (II) Multiple detections Ru(bpy)32+ electrochemiluminescence

SCI ; EI

英语

第一 ; 通讯

National Natural Science Foundation of China[22074059] ; Guangdong Basic and Applied Basic Research Foundation[2021A1515010145]

Chemistry ; Electrochemistry

Chemistry, Analytical ; Electrochemistry

WOS:000767853100004

ELSEVIER SCIENCE SA

20214911259380

Citrus fruits ; Cost effectiveness ; Density functional theory ; Mercury compounds ; Metal ions ; Metals ; Neurophysiology

Medicine and Pharmacology:461.6 ; Metallurgy:531.1 ; Organic Compounds:804.1 ; Agricultural Products:821.4 ; Industrial Economics:911.2 ; Probability Theory:922.1 ; Atomic and Molecular Physics:931.3 ; Quantum Theory; Quantum Mechanics:931.4

CHEMISTRY

2-s2.0-85120309905

Scopus

1.Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China
2.State Key Laboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,5625 Renmin Street,130022,China
3.Faculty of Science,Department of Mathematics,University of Gujrat,Gujrat,50700,Pakistan
4.Department of Physics,Southern University of Science and Technology,Shenzhen,518055,China

Saqib，Muhammad,Bashir，Shahida,Ali，Sajjad,et al. Highly selective and sensitive detection of mercury (II) and dopamine based on the efficient electrochemiluminescence of Ru(bpy)32+ with acridine orange as a coreactant[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY,2021,906.

Saqib，Muhammad,Bashir，Shahida,Ali，Sajjad,&Hao，Rui.(2021).Highly selective and sensitive detection of mercury (II) and dopamine based on the efficient electrochemiluminescence of Ru(bpy)32+ with acridine orange as a coreactant.JOURNAL OF ELECTROANALYTICAL CHEMISTRY,906.

Saqib，Muhammad,et al."Highly selective and sensitive detection of mercury (II) and dopamine based on the efficient electrochemiluminescence of Ru(bpy)32+ with acridine orange as a coreactant".JOURNAL OF ELECTROANALYTICAL CHEMISTRY 906(2021).