题名 | CasX: a new and small CRISPR gene-editing protein |
作者 | |
通讯作者 | Yang, Hui; Patel, Dinshaw J. |
发表日期 | 2019-05
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DOI | |
发表期刊 | |
ISSN | 1001-0602
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EISSN | 1748-7838
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卷号 | 29期号:5页码:345-346 |
摘要 | In a recent paper published in Nature, Liu et al. demonstrate the DNA cleavage characteristics of CasX (a newly identified dual-RNA-guided DNA targeting nuclease) and establish its capacity for genome editing in Escherichia coli and human cells. Furthermore, they capture structural snapshots of CasX in different states by cryo-EM and establish a model of RNA assembly, DNA targeting and sequential cleavage. |
相关链接 | [来源记录] |
收录类别 | |
语种 | 英语
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学校署名 | 通讯
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WOS研究方向 | Cell Biology
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WOS类目 | Cell Biology
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WOS记录号 | WOS:000466153400004
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出版者 | |
ESI学科分类 | MOLECULAR BIOLOGY & GENETICS
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来源库 | Web of Science
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引用统计 |
被引频次[WOS]:19
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成果类型 | 期刊论文 |
条目标识符 | http://sustech.caswiz.com/handle/2SGJ60CL/26003 |
专题 | 生命科学学院_生物系 |
作者单位 | 1.Chinese Acad Sci, Univ Chinese Acad Sci, State Key Lab Mol Biol, CAS Ctr Excellence Mol Cell Sci,Shanghai Inst Bio, Shanghai 200031, Peoples R China 2.Mem Sloan Kettering Canc Ctr, Struct Biol Program, New York, NY 10065 USA 3.Southern Univ Sci & Technol, Dept Biol, Shenzhen 518055, Guangdong, Peoples R China |
通讯作者单位 | 生物系 |
推荐引用方式 GB/T 7714 |
Yang, Hui,Patel, Dinshaw J.. CasX: a new and small CRISPR gene-editing protein[J]. CELL RESEARCH,2019,29(5):345-346.
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APA |
Yang, Hui,&Patel, Dinshaw J..(2019).CasX: a new and small CRISPR gene-editing protein.CELL RESEARCH,29(5),345-346.
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MLA |
Yang, Hui,et al."CasX: a new and small CRISPR gene-editing protein".CELL RESEARCH 29.5(2019):345-346.
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条目包含的文件 | 条目无相关文件。 |
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