Low-modulus biomedical Ti-30Nb-5Ta-3Zr additively manufactured by Selective Laser Melting and its biocompatibility

Luo, J. P.1,2; Sun, J. F.1; Huang, Y. J.1; Zhang, J. H.2; Zhang, Y. D.3; Zhao, D. P.4; Yan, M.2

2019-04

10.1016/j.msec.2018.11.077

Materials Science & Engineering C-Materials for Biological Applications   影响因子和分区

0928-4931

1873-0191

Low Young's modulus titanium alloys, such as Ti-30Nb-5Ta-3Zr (TNTZ) of this study, were promising biocompatible implant materials. In this work, TNTZ samples with relative density of 96.8%-99.2% were additively manufactured by powder-bed based Selective Laser Melting (SLM) through tuning processing parameters, i.e. varying the point distance between 50 and 75 mu m, laser exposure time between 135 and 200 us, and a fixed laser power of 200 W. The microstructure, elastic properties, fatigue properties and machining accuracy of the fabricated samples have been investigated. Lattice structure TNTZ samples with porosity of 77.23% were also fabricated to further reduce the Young's modulus of the TNTZ. According to the Relative Growth Rate (RGR) value, the as-printed TNTZ samples exhibited no cell cytotoxicity, where they showed even better biocompatibility than the comparative, as-printed Ti-6Al-4V samples. The as-printed TNTZ developed by the study demonstrates good biocompatibility, low stress shielding tendency and high mechanical properties.

Selective Laser Melting TNTZ Biocompatibility Mechanical properties Microstructure

SCI ; EI

英语

通讯

Natural Science Foundation of Guangdong Province[2016A030313756]

Materials Science

Materials Science, Biomaterials

WOS:000457952800026

ELSEVIER SCIENCE BV

20185106271018

3D printers ; Additives ; Aluminum alloys ; Biocompatibility ; Biological materials ; Elastic moduli ; Growth rate ; Machining ; Mechanical properties ; Melting ; Microstructure ; Niobium alloys ; Tantalum alloys ; Ternary alloys ; Zirconium alloys

Biological Materials and Tissue Engineering:461.2 ; Immunology:461.9.1 ; Aluminum Alloys:541.2 ; Titanium and Alloys:542.3 ; Tantalum and Alloys:543.4 ; Nonferrous Metals and Alloys excluding Alkali and Alkaline Earth Metals:549.3 ; Machining Operations:604.2 ; Printing Equipment:745.1.1 ; Chemical Operations:802.3 ; Chemical Agents and Basic Industrial Chemicals:803 ; Materials Science:951

Web of Science

1.Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Heilongjiang, Peoples R China
2.Southern Univ Sci & Technol China, Shenzhen Key Lab Addit Mfg High Performance Mat, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China
3.South Univ Sci & Technol China, Dept Biol, Shenzhen 518055, Peoples R China
4.Hunan Univ, Coll Biol, Changsha 410082, Hunan, Peoples R China

Luo, J. P.,Sun, J. F.,Huang, Y. J.,et al. Low-modulus biomedical Ti-30Nb-5Ta-3Zr additively manufactured by Selective Laser Melting and its biocompatibility[J]. Materials Science & Engineering C-Materials for Biological Applications,2019,97:275-284.

Luo, J. P..,Sun, J. F..,Huang, Y. J..,Zhang, J. H..,Zhang, Y. D..,...&Yan, M..(2019).Low-modulus biomedical Ti-30Nb-5Ta-3Zr additively manufactured by Selective Laser Melting and its biocompatibility.Materials Science & Engineering C-Materials for Biological Applications,97,275-284.

Luo, J. P.,et al."Low-modulus biomedical Ti-30Nb-5Ta-3Zr additively manufactured by Selective Laser Melting and its biocompatibility".Materials Science & Engineering C-Materials for Biological Applications 97(2019):275-284.