南方科技大学知识苑(SUSTech KC): SCREENING BREAST LESIONS USING SHEAR MODULUS AND ITS 1-MM SHELL IN SOUND TOUCH ELASTOGRAPHY

题名	SCREENING BREAST LESIONS USING SHEAR MODULUS AND ITS 1-MM SHELL IN SOUND TOUCH ELASTOGRAPHY
作者	Zhang, Lei 1,2 ; Xu, Jinfeng 1; Wu, Huaiyu 1; Liang, Weiyu 1; Ye, Xiuqin 1; Tian, Hongtian 1; Dong, Fajin 1
通讯作者	Dong, Fajin
发表日期	2019-03
DOI	10.1016/j.ultrasmedbio.2018.11.013
发表期刊	ULTRASOUND IN MEDICINE AND BIOLOGY 影响因子和分区
ISSN	0301-5629
EISSN	1879-291X
卷号	45 期号:3页码:710-719
摘要	The aim of the study described here was to screen breast lesions using either or both shear modulus (G) and its 1-mm shell (S) in sound touch elastography through a retrospective study of 209 consecutive women with breast lesions. The ability of G and S data to differentiate between malignant and benign lesions was evaluated using the receiver operating characteristic (ROC) curve. The optimal cutoff point, sensitivity, specificity, positive likelihood ratio (LR+) and negative likelihood ratio (LR-) were calculated. Then, the parameters were pooled to determine the area under the summary receiver operating curve (AUSROC). The pooled sensitivity (PSen), pooled specificity (PSpe), pooled LR+ (PLR+), pooled LR- (PLR-) and diagnostic score (DS) were calculated. Pathologic examination results were used as the reference. In total, 209 patients with 155 benign and 54 malignant lesions were enrolled. For G(max), G(mean) and G(sd), the cutoff values were 35.15 kPa (p = 0.0001), 10.18 kPa (p = 0.0001) and 5.18 kPa (p = 0.0001), respectively. For S-max, S-mean and S-sd, the cutoff values were 40.94 kPa (p = 0.001), 13.12 kPa (p = 0.0001) and 7.97 kPa (p = 0.0001), respectively. There were no significant differences in G(min) and S-min between benign and malignant lesions. For the pooled six parameters, the PSen, PSpe, PLR+, PLR-, DS and AUSROC were 86% (95% confidence interval: 82%-89%), 82% (80%-85%), 4.90 (4.24-5.68), 0.17 (0.13-0.22), 3.36 (3.00-3.72) and 91% (88-93%), respectively. The G and S parameters of sound touch elastography could provide valuable data for the evaluation of breast lesions. Additionally, use of multiple parameters or combined use of the six parameters may be more effective in the evaluation of breast lesions. (C) 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
关键词	Ultrasonography Elasticity imaging techniques Sound touch elastography Shear modulus Breast cancer Diagnosis
相关链接	[来源记录]
收录类别	SCI ; EI
语种	英语
学校署名	第一 ; 通讯
资助项目	Clinical Project of Shenzhen People's Hospital[SYLY201702]
WOS研究方向	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000457853400010
出版者	ELSEVIER SCIENCE INC
EI入藏号	20190206361262
EI主题词	Diagnosis ; Elastic moduli ; Parameter estimation ; Scattering parameters ; Shear strain ; Touch screens ; Ultrasonography
ESI学科分类	CLINICAL MEDICINE
来源库	Web of Science
引用统计	被引频次[WOS]：9
成果类型	期刊论文
条目标识符	http://sustech.caswiz.com/handle/2SGJ60CL/26308
专题	南方科技大学第一附属医院
作者单位	1.Jinan Univ, Clin Coll 2, Southern Univ Sci & Technol,Shenzhen Peoples Hosp, Dept Ultrasound,Affiliated Hosp 1,Shenzhen Med Ul, Shenzhen 518020, Peoples R China 2.Guangzhou Med Univ, Guangzhou, Guangdong, Peoples R China
第一作者单位	南方科技大学第一附属医院
通讯作者单位	南方科技大学第一附属医院
第一作者的第一单位	南方科技大学第一附属医院
推荐引用方式 GB/T 7714	Zhang, Lei,Xu, Jinfeng,Wu, Huaiyu,et al. SCREENING BREAST LESIONS USING SHEAR MODULUS AND ITS 1-MM SHELL IN SOUND TOUCH ELASTOGRAPHY[J]. ULTRASOUND IN MEDICINE AND BIOLOGY,2019,45(3):710-719.
APA	Zhang, Lei.,Xu, Jinfeng.,Wu, Huaiyu.,Liang, Weiyu.,Ye, Xiuqin.,...&Dong, Fajin.(2019).SCREENING BREAST LESIONS USING SHEAR MODULUS AND ITS 1-MM SHELL IN SOUND TOUCH ELASTOGRAPHY.ULTRASOUND IN MEDICINE AND BIOLOGY,45(3),710-719.
MLA	Zhang, Lei,et al."SCREENING BREAST LESIONS USING SHEAR MODULUS AND ITS 1-MM SHELL IN SOUND TOUCH ELASTOGRAPHY".ULTRASOUND IN MEDICINE AND BIOLOGY 45.3(2019):710-719.